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Patients subject to MET review have a high in-hospital mortality (20%). Thus, understanding the outcome of patients within the first 24hr of MET review is important in developing quality improvement and interventional studies to reduce this…
The hypothesis of the present study is to demonstrate that detection of a particular pattern (e.g., persistent vs. non-persistent) of myocardial (alpha)V(beta)3/5 expression by scintigraphy imaging at 3 and 8 weeks after MI can be used to determine…
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
We hypothesize that clinicians exposed to this intervention are more likely to adopt SDM behaviors than clinicians who do not. A secondary aim is to evaluate whether patients perceive more involvement in the decision-making process.
It is increasingly recognized that the immune system is a major player in this obesity related disease and the switch from benign to malign (insulin resistance and DM2) obesity is associated with changes in the immune system . In this regard, animal…
An early mobilization program in critically ill children reduce the consumption of sedatives and opioids and the prevalence of delirium.
In non-COVID-19 patients with pulmonary embolism a prevalence of up to 70% of concomitant symptomatic or asymptomatic deep venous thrombosis has been reported. Physicians experience an exceptionally high prevalence of pulmonary embolism in COVID-19…
A conservative approach, rather than surgical resection, is safe for non-functioning grade 1 and 2 pancreatic neuroendocrine tumors <2cm.
MBSR influences (1) emotional processing and (2) body awareness. The effect of MBSR on emotional processing is (3) mediated by body awareness.
We aim to compare the accuracy of ultrasound derived blood flow parameters from the carotid artery to pulse-contour derived cardiac output and non-invasive cardiac output measurements. Our motivation is to develop a non-invasive, radiation-free,…
Prospective study determing whether MRI-Diffusion Weighted Imaging (DWI) and biomarkers in CSF have prognostic capabilities in patients with Spinal Cord Injury (SCI).
Due to surgery and radiotherapy lymph drainage pathways in recurrent breast cancer could be altered. These aberrant drainage pathways could be detected with lymphatic mapping and sentinel node biopsy leading to a more thorough staging and possible…
We expect that mp-MRI, molecular urine test and Prostate Cancer Risk Calculator may be of additional value in differentiating between significant and insignificant cancers in men with an elevated PSA in the primairy diagnosis. If so, it will result…
Outpatient LMHW treatment in patients with objectively proven non-massive pulmonary embolism is efficacious and safe.
The primary objective is to prospectively identify cardiac damage in childhood cancer patients, during and shortly after treatment with anthracyclines.
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
The primary objective of this study is to explore the correlation between invasive and non-invasive haemodynamic variables and monitor the effect of treatment during admission for acute decompensated heart failure. In particular to investigate…
To assess the change in voiding pattern and quality of life in children who receive BoNT-A treatment in a prospective setting.
To elongate the service life of the implantable neurostimulator while achieving a minimal improvement of 50% of the symptoms of overactive bladder compared to baseline.