105 resultaten
RRT activation rate within a hospital or wards within a hospital are likely to be associated with specific factors regarding possible delay in escalation of care for deteriorating patients. This research is focussed on elucidating factors which may…
- Hypothesis#1 efficacy We hypothesize that a quick onset, and a predictable dose-response, good adjustability of analgesia can be achieved with inhaled ketamine. Hypothesis#2 safety Inhalation of nebulized ketamine might lead to a fast onset of…
Perfusion Angiography, in relation with known parameters, describes the ultimate prognostic model in revascularized Critical Limb Ischemia patients.
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
Patients subject to MET review have a high in-hospital mortality (20%). Thus, understanding the outcome of patients within the first 24hr of MET review is important in developing quality improvement and interventional studies to reduce this…
We expect that mp-MRI, molecular urine test and Prostate Cancer Risk Calculator may be of additional value in differentiating between significant and insignificant cancers in men with an elevated PSA in the primairy diagnosis. If so, it will result…
The primary objective of this study is to explore the correlation between invasive and non-invasive haemodynamic variables and monitor the effect of treatment during admission for acute decompensated heart failure. In particular to investigate…
To evaluate the diagnostic accuracy (distress recognition) of the new procedure for detecting psychological distress in patients with cancer
Metabolic disturbances associated with critical illness may disturb secretion of melatonin, the most important factor for circadian timekeeping. This disturbance may in turn hamper distribution and high quality sleep, with potentially detrimental…
Combining FOLFIRINOX chemotherapy and stereotactic radiotherapy can lead to better regional tumor control and better overall survival in patients with locally advanced pancreatic cancer.
First, non-invasive diagnostic tools can optimize the diagnostic strategy, in order to minimize the number of invasive diagnostic procedures. Second, invasive imaging of the pulmonary artery can further differentiate the mechanisms involved in PH…
The aim of the study is to develop a screening tool to identify young children at risk of posttraumatic stress disorder following an accident.
We hypothesize that the deformation-area curves will show an alteration in the relationship between deformation and area for the differing (pressure or volume related) cardiovascular diseases
A one-day-visit systematic assessment in a specialized severe asthma centre contributes to improvement in asthma control, quality of life and healthcare utilization.
Rationale: Hypertension is the most common cardiovascular condition responsible for the development and maintenance of atrial fibrillation (AF). Treating drug-resistant hypertension with renal denervation has been reported to control blood pressure…
Objectives: 1) To describe the incidence and severity of cognitive impairments in patients with glioma and meningiomas before, and 3 and 12 months after surgical treatment. 2) To develop models based on presurgical sociodemographic, clinical,…
The primary objective of this study is to reduce the number of patients with at least one event when using the CRR (a computerised clinical descion support system) compared to the regular care. These events consist of hospital referrals, delirium,…
This evaluation does not have a hypothesis to be tested since it is intended to evaluate the workflow and usability of the new software solution, without prior defined performance criteria.
The hypothesis is that a graded physical exercise program in which strength and endurance are trained have a positive effect on fatigue after stroke measured with the CIS-f (Checklist Individual Strength subscale fatigue) or FSS-7 (Fatigue Severity…
A more rapid rise of the levodopa plasma level after inhalation compared to oral administration of levodopa.