47 resultaten
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
Current standard treatments for symptomatic benign thyroid nodules (SBTN) are surgery or radioactive iodine. However, these interventions pose a risk to an otherwise healthy person. Therefore, minimally invasive alternatives have been explored.…
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research
Impairment of immune-complex-induced neutrophil activation caused by PDE4 inhibition, making it a potential target for the treatment of pemphigoid diseases.
The hypothesis addressed in this project is that serum calcification propensity is a predictor of coronary artery calcification progression.
The aim of the project is to gain insight into the effects of centralisation of polytrauma care on the quality of care. We also want to investigate the effect on the quality and quantity of regular trauma care by shifting polytrauma care from…
The dutch language version of the PRHWE and the Quick DASH questionnaire are valid to use in patients with hand and wrist complaints
The absolute bioavailability of oral imatinib (Glivec®) at steady state can be calculated using LC-MS/MS after concomitant administration of a single 100 µg microdose of stable isotope labeled imatinib (imatinib-d8).
Our hypothesis is that despite advanced laboratory techniques serum levels of amylase/lipase are <3 times ULN in patients presenting with hypertriglyceridemia during acute pancreatitis.
We hypothesize that socioeconomic inequalities in diet quality are partly explained by differential dietary costs.
The purpose of this study is to evaluate toxicity and oncologic outcomes of MRI-guided focal salvage high-dose-rate brachytherapy (HDR-BT). In earlier studies, it was shown that focal salvage HDR-BT is feasible and results regarding toxicity are…
By giving high dose, radical, radiotherapy to patients with recurrent lung cancer, the overall survival can be prolonged and local control rate can be increased which can be done with acceptable toxicity for the irradiated normal tissues.
Difference in phenotype between nonbullous and bullous pemphigoid can be explained by gene expression and/or eosinophillic activity in the skin.
We hypothesise that the relations of total fat and fatty acid (FA) subtypes (SFA, MUFA, or PUFA) with CHD are modified by their food source. We aim to directly compare relations of FA subtype intake from dairy and meat with risk of CHD by using…
The gastric balloons are expected to remain in the stomach for approximately four weeks, after which they burst and are fecally excreted. It is further hypothesised that intragastric balloons can provide a surrogate stomach fill, inducing an…
The main objective of this study is to compare upper extremity dysfunction (UED) following slender TRPCI using small bore catheters (5F) compared to standard PCI using regular size guiding catheters (6F) and conventional stent techniques at two…
Tacrolimus (FK506) is the main immunosuppressant that is prescribed after kidney transplantation. One of the disadvantages of Tacrolimus is the small therapeutic window. In transplantation patients therapeutic drug monitoring is routinely performed…