41 resultaten
Type 2 diabetes is cause by progressive beta-cell dysfunction against a background of obesity and insulin resistance in susceptible individuals. Peroxisome proliferator-activated receptor (PPAR) gamma-mediated mechanisms are involved in the…
Develop a screening tool to identify children at risk of posttraumatic stress disorder after an accident.
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
By using a surgical safety checklist, the incidence of postoperative complications will decrease.
1. Regular physical follow-up can partly be replaced by nurse-led telephone follow-up, with at least similar quality of life (QoL), in breast cancer patients treated with curative intent. ( change in QoL < 5 points) 2. An informative/…
We expect that there will be a restrictive condition in the first place. After a longer period there may be an obstructive condition, due to the original infection. We expect that the leucocyte count of the pleural fluid, the number of loculations…
To determine the sensitivity and specificity and positive and negetive predictive value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis.
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of midazolam.
With postoperative minimal enteral feeding (MEF) the neonates can be fed completely enteral earlier than without MEF.
The majority of newly diagnosed cancer patients are >65 years of age. Elderly patients are more vulnerable than younger ones, due to comorbidities and frailty. Their treatment goals and preferences may also differ greatly. This study uses a…
In this single subject study we would like to determine whether parameter optimizing is feasible. Furthermore we want to investigate whether patients with urge symptoms have optimal benefit from different parameters than patients with non-…
1. The recognition of malnourished inpatients will improve by using the SNAQ malnutrition screening tool at admission; 2. Early recognition and treatment of malnutrition is effective and cost effective.
We expect that when the developed checklist will be used in de diagnostic proces of children with developmental and/or behavioral disability, the use of pediatric care will be more efficiently used. Over and underdiagnoses of a causal somatic…
No improvement of fixation failure will be found after the introduction of the TFNA
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
Opening wedge HTO treated with DBM will better match one year post-operative mechanical axis alignement with pre-operative planned correction then opening wedeg HTO filled with autogenous iliac crest bone.
Our hypothesis is that the iron status in young healthy children from the Netherlands might be insufficient.
We hypothesise that CAP is a safe treatment that reduces bacterial load on the wound surface and promotes wound healing.
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.