23 resultaten
The primary goal is to show the capability of monocyte-derived DC after RNA electroporation for multiple antigens to induce an immune response. The secondary objective is to show clinical response.
In this single subject study we would like to determine whether parameter optimizing is feasible. Furthermore we want to investigate whether patients with urge symptoms have optimal benefit from different parameters than patients with non-…
We hypothesize that the commercially available CE-marked over the scope Pro-select Padlock clip is able to clip a gastic/duodenal SET, where after full thickness resection of the SET can be achieved using a normal
The aim of this research project is to investigate cannabidiol as a new medicine to target the cannabinoid system in the reduction of anxiety disorder symptoms. The research question is whether cannabidiol, as an augmentation strategy of exposure…
The primary objective is to determine the efficacy of angina control with this type of Peripheral Subcutaneous Field Stimulation (PSFS) at three months and 12 months. This will be assessed in a patient diary by the number of angina attacks and the…
Alemtuzumab induction therapy in ABOi kidney transplantation lowers the incidence of cellular-mediated BPAR compared to rituximab induction, without affecting the number of antibody-mediated rejections.
The effectiveness of a health game based on an Evaluative Conditioning paradigm compared to a control game will be tested in a Dutch sample of adolescents. It is expected that the adolescents in the intervention condition will show a increased…
The objective is to investigate the effect of cannabidiol (synthetic) as compared to placebo in facilitating fear extinction and reducing fear retention and reinstatement.
Certain patient-specific factors contribute significantly to the outcome of delivery after a cesarean section in a Dutch hospital setting. These factors influence the decision to initiate trial of labour (TOL) or plan for an elective repeat…
Acidic and neutral oligosaccharides supplemented enteral nutrition has a positive effect on infectious morbidity, modulation of the immune response, postnatal adaptation of the gut, feeding tolerance and short-term outcome in VLBW infants.
Essess the effectiveness of the Xience stent compared to the CYPHHER stent in the treatment of acute myocardial infarction patients.
Project goal: To increase the percentage of HIV-infected immigrant patients with an HIV-RNA <20 copies/ml (successful treatment) and to reduce the transmission of HIV within this ‘key population’(non-European immigrants). Additionally,…
The general objective of the DECREASE-IV trial is to assess the clinical efficacy of beta-blocker therapy, statin therapy and combination therapy with beta-blockers and statins in patients undergoing major noncardiac surgery.
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
We hypothesise that CAP is a safe treatment that reduces bacterial load on the wound surface and promotes wound healing.
the use of a digital electrocardiogram in general practice attributes to the detection of silent ischemia
Inflammatory injury of the lung after cardiac surgery in heart failure versus non-heart failure patients; An observational study of clinical variables, genetic association, and etiologic and prognostic aspects of inflammatory markers in serum and…
1. After completing real approach bias re-training, participants will show a stronger reduction in approach bias for alcohol than after placebo training (main effect 1); 2. After completing real attentional bias re-training, participants will show a…
1. Women in the CBT group, the PE group or the combined CBT-PE group (groups A, B and AB) will report significantly greater reduction from baseline to 3 and 6 month follow-up in overall levels of menopausal symptoms than patients in a usual care,…