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1. Regular physical follow-up can partly be replaced by nurse-led telephone follow-up, with at least similar quality of life (QoL), in breast cancer patients treated with curative intent. ( change in QoL < 5 points) 2. An informative/…
Evaluation of efficacy and safety of two different formulas of alfa-Galactosidase A, agalsidase beta (FabrazymeTM) and agalsidase alpha (ReplagalTM) in an equal dose of 0,2 mg/kg in order to detect any differences between these two drugs.
Combination of a round window insertion approach and a lateral wall electrode array minimizes insertion trauma
Opening wedge HTO treated with DBM will better match one year post-operative mechanical axis alignement with pre-operative planned correction then opening wedeg HTO filled with autogenous iliac crest bone.
1. The recognition of malnourished inpatients will improve by using the SNAQ malnutrition screening tool at admission; 2. Early recognition and treatment of malnutrition is effective and cost effective.
We will test whether each component specifically reduces the risk factor it aims to target: Does component A (relational perspective based child-led play) improve the parent-child relationship, and not coercive parent-child interaction cycles or…
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.
Research Question 1: Do mental health apps improve mental wellbeing? This question will be investigated by testing the following hypothesis: There will be an interaction between condition (allocation to one of the 4 apps vs. no-app control; between…
No improvement of fixation failure will be found after the introduction of the TFNA
We will identify clinical and cancer treatment related risk factors associated with hearing loss, tinnitus and vertigo. We will determine the prevalence of hearing loss, tinnitus and vertigo in a prospective cohort of CNS/ solid tumor patients.
A self-management program including self-treatment of exacerbations, leads to a reduction in the severity and duration of exacerbation compared to a similar self-management program without these self-treatment guidelines in hospital out-patients…
A 10% point difference between the experimental groups and control group in MPV uptake is expected.
Botulinum toxin A declines the severity of tardive dyskinisias.
Biomarkers like MR-proADM and CT-proAVP predict severity and outcome in critically ill COVID-19 patients. MR-proADM and CT-proAVP at admittance can be higher in non-survivors and biomarker clearance over the days will be higher in survivors.
Exploratory. To explore the effects on breast development of addition of progesterone to the treatment with estradiol in trans women after vaginoplasty or orchiectomy. Secondary objectives include safety and patient satisfaction, mood, and sleep.
Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.
A therapeutic language and communication training using VR helps OR-staff to diminish patients anxiety levels before going into surgery.
Preoperative physiotherapy decreased the incidence of postoperative pulmonary complications (PPCs) after open heart surgery on patients with an increased risk of developing PPCs.
To what extent will the introduction of the C-Reactive Protein (CRP) point of care test and enhanced communication skills for managing lower respiratory tract infection (LRTI) in general practice, either separately or combined, lead to 1. an…
Our hypothesis is that treatment with micrografting, when compared to conventional meshed graft, will result in a better scar quality and smaller donor site size.