316 resultaten
Paricalcitol induces a more effective reduction of the PTH level than alfacalcidol in hemodialysis pa-tients with secondary hyperparathyroidism NL Paricalcitol geeft een effectievere daling van de PTH spiegel ten opzichte van alfacalcidol bij hemodi…
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In this randomized crossover pharmacokinetic study we will investigate the effects of cytochrome P450 enzyme induction (including CYP3A4, CYP2C and CYP2D6) by rifampicin on the metabolism and plasma pharmacokinetics of tamoxifen and its metabolites…
The 3 new developed prototype electric brush heads (A,B,C) remove 15% more plaque compared to a EB17 brush head
Primary Objective: In this trial we will investigate the efficacy of BVR using best responder criteria in patients with severe heterogeneous emphysema compared to usual care. Secondary Objective: Economic evaluation: Estimation of costs of BVR…
The efficacy of reflux inhibitors, which block transient lower esophageal sphincter relaxations (TLESRs), to reduce acid and non-acid exposure may be hampered in the presence of a hiatal hernia, as other mechanisms of reflux become more important.
1. Participation in an early home-based education programme compared to care as usual will significantly increase knowledge on kidney disease and treatment options, communication on renal replacement options and promote a positive attitude towards…
Our hypothesis is that the satiating capacity of protein is partly regulated via the savoury signal of foods. We therefore expect that the savoury diet is more satiating than the sweet diet and the control diet, resulting in a decreased intake after…
Phytosphingosine decreases cholesterol levels and improves insulin sensitivity
Compared to treatment as usual implementing Integrated Double Diagnosis Treatment (IDDT) in mental health care teams for severe mental illness (SMI) outpatient will improve a. outcomes at psychiatric symptoms and drug or alcohol abuse, and b. will…
Doxycycline will ameliorate the vascular condition and inflammatory status in patients with mild to moderate atherosclerotic disease
To investigate if flavour nutrient learning is an effective mechanism to increase children's vegetable intake. Is there an effect?
Are there effects of ARA290 and Epo on the ventilatory response to hypoxia. Are there effects of ARA290 and Epo on the gradient over the tricuspid valve during hypoxia a an estimation of the pulmonary artery pressure (PAPA). Does ARA290 and/or Epo…
We hypothesise that there is a central mechanism that shuts down energy consumption by brown adipose tissue (BAT) during hypoglycaemia. This could be a mechanism to protect the brain from neuroglycopenia.
5 and 10 grams of a protein hydrolysate effectively increase insulin secretion and lowers plasma glucose levels after a carbohydrate load in type 2 diabetes mellitus (DM-2)
We hypothesized that FFA loading could impair mitochondrial function and that the potency of FFA to disturb mitochondrial function and glucose uptake would depend on the degree of desaturation of the fatty acids infused.