160 resultaten
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…
A 4-month WFPD H0: has no effect on the levels of serum uric acid in patients with gout, hyperuricemia and abdominal obesity in comparison with usual care. H1: results in decreased levels of serum uric acid in patients with gout, hyperuricemia and…
To demonstrate wether there is difference in tissue oxygen tension and extravascular lung water while patients are being resuscitated with cristalloids or colloids combined with cristalloids.
A self help brochure will help people decrease their excessive worrying. and telephonic support will increase the effect.
Inhalation of rhDNase before sleep increases the expiratory flow at 25% of the actual forced vital capacity (MEF25) compared to inhalation of rhDNase in the morning.
The higher hardness/protein density of protein gel would delay gastric emptying and protein hydrolysis in humans; MRI technique can used to monitor gastric digestion (in this case: protein hydrolysis) in humans.
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
We hypothesised that this strategy could lead to a considerable and relevant change of prescribing behaviour in the desired direction.
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
Which design of cognitive aid (emergency manual) is easier to use and results in less missed critical actions during anesthetic emergencies
Better glucose control during the closed loop system compared to standard open loop therapy
We hypothesize that the MMP could be cost-efficient for a part of the patients, but that for some patients a more simple prosthesis would be more cost-efficient. Therefore, we do not expect big differences in cost-effectiveness between the MMP and…
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
Interindividual variation in antihypertensive drug response can be predicted through lifestyle, demographics and plasma drug levels.
Cannabinoid receptor (CB1) agonists, like marinol, lower the rate of TLESRs and can be useful in the treatment of gastroesophageal reflux disease (GERD).
A nursing nutrition intervention improves protein and energy intake and performance based on hand grip strength compared to usual care.
Use of any mask (surgical or N95) in a standard day of work for hospital staff, may result in subjective feelings of dyspnoea. These symptoms of dyspnoea do not correlate to a decreased oxygen saturation, but do correlate to baseline participant…
We hypothesize that methylphenidate improves ADHD manifestations in children and adults with SMS.