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Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
Preoperative planning with x-ray-based PSI have comparable outcome as 3D used MRI-based PSI resulting in indirectly reduced costs on storage of implants and instruments.
It is hypothesized that the outcome of the primary outcome parameter will be different for the test product compared to the control product.
Preterm infants often require supplemental oxygen to prevent hypoxemia and hyperoxemia. Conditions that have been associated with organ damage and an increased mortality. Newly developed techniques incorporated in the ventilator provide the…
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We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
The hypothesis formulation for the primary outcome parameter is: -H0: The effect of using test product (Product A) is equal to the effect of using control product (Product B) with respect to the area under the curve (AUC(0-360))of serum P. -H1: The…
We expect that younger children have a higher learning capacity at the end-effector level, thus they should be faster in learning to handle the visuomotor transformation task than older children.
Doxepin hydrochloride 5% cream significantly reduces pruritus in burn patients in comparison with a placebo cream
Patients with ALS are routinely prescribed riluzole, the only registered drug for the treatment of ALS. This study will evaluate the concentration-effect relationship of riluzole (100 mg) and retigabine (300 mg) on axonal excitability measures. In…
To determine the influence of curcumin and piperine on tamoxifen pharmacokinetics.
A soft brace will improve pain, knee instability and activity limitations in the study participants with knee ostoearthritis.
Vascular function improves after a reduced sitting intervention
Contaminated duodenoscopes can cause large-scale outbreaks. There is a need for rapid assessment methods to confirm the adequacy of the cleaning phase to improve the quality, safety and logistics of complex flexible endoscope reprocessing. The ATP…
The aim of present study is to assess the effect of a patient information portal on patient information and shared decision-making in a multicenter stepped-wedge cluster randomized trial.
Reduced tremor power during transcranial alternating current stimulation over primary motor cortex (at tremor frequency and phase-locked to the ongoing tremor).
The use of incisional management system reduces the incidence of wound dehiscence in low and high-risk patients undergoing plastic surgery.
Objective: The overall aim of this project is to asses the characteristic changes of the strain-volume loop, after acute, physiological-induced, changes in afterload. We hypothesize that the strain-volume loop will present a leftward shift in case…
The primary objective of this study is to investigate if a specifically designed VR-game is able to activate the pathophysiological substrate associated with OCD in OCD patients, as opposed to healthy controls. This will be investigated by…