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The flavonoid-drug interaction could potentially lead to higher nintedanib absorption by the gastro-intestinal tract. This would cause higher systemic bioavailability and lower local gastro-intestinal drug concentrations. Furthermore, inter-patient…
Adding specific components designed to target three risk factors for child maltreatment (parental stress, parental anger, and post-traumatic stress symptoms) to an evidence-based home visiting program alleviates these specific risk factors.
exercise improves social functioning, quality of life and decreases symptom severity
Our hypothesis is that growth hormone threatment in adults with Prader-Willi Syndrome will improve their metabolic and cardiovascuar health, thereby resulting in a reduced mortality.
The post-prandial rise in total amino acid, proline and glycine concentration following a single bout of resistance exercise will be the highest in the 20 gr whey combined with 10 gr collagen compared to all other test drinks
High BMI is associated with worst prognosis after SARS-CoV2 infection
Overall, diagnostic accuracy will be lower on subjected-to-bias than on not-subjected-to-bias cases, but the difference in accuracy will be smaller in the group of physicians with higher knowledge of critical diagnostic features. Overall, the…
A 10% point difference between the experimental groups and control group in MPV uptake is expected.
Polystyrene sulfonate shows an in-vitro binding interaction with amitriptyline, causing 70-80% binding of amitriptyline to polystyrene sulfonate. The hypothesis is that polystyrene sulfonate binds to amitriptyline when taken simoultaneously in…
Curcumin is expected to have a positive effect in the composition of gut microbiota and the measurable outcomes of this change in composition.
The intended research aims to evaluate whether a better suppression of adrenal androgens, so a better hormonal setting, can be achieved by changing the time of the highest dose in the morning or in the evening.
1. The addition of moderate positive end-expiratory pressure (PEEP, 7.5 cmH2O) to high inspiratory fractions of oxygen can either improve oxygenation or reduce respiratory rate, or both, in patients with severe Covid-19 pneumonia 2. The application…
Using inhaled volatile anaesthetic agents as the primary sedative during mechanically ventilation in patients with COVID-19-associated ARDS improves gas exchange and ventilatory support requirements
Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.
Our hypothesis is that treatment with micrografting, when compared to conventional meshed graft, will result in a better scar quality and smaller donor site size.
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
2C-B generates distinct acute and subacute effects from Psilocybin and placebo
The hypothesis of this study is that implementation of an evidence-based management algorithm to standardize care will improve the level of care, lower the complication rate and improve the quality of life for patients with chronic pancreatitis.
It is expected that patients prefer the AFO with the best efficacy, and that the preference is reliable at the moment of AFO fitting.