1011 resultaten
1. The primary research inquiry being raised concerns anaesthesia related causes: Is it possible that adapting an amount of Sevoflurane, from 1 MAC (minimum alveolar concentration) (2,5 vol%) to ½ MAC (1,25 vol%) in an MRI scan can reduce the…
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The aim of the meta-analysis is to investigate the early predictive value of migration measured by RSA 1 year post-operatively for revision for aseptic loosening of the femoral component in THA and to compose migration thresholds for safe and…
Artificial dynamic lightening can positively influence the sleep/wake cycle and reduce the disturbance of the circadian rhythm due to hospitalization.
This study evaluates the beneficial effects of exercise training with or without oral anti-diabetic medication in patients with coronary artery disease (CAD): PCI or CABG in stable CAD, or post STEMI and post non-STEMI patients who have pre-diabetes…
Acetaminophen is effective in treating self-reported sleep problems, in particular insomnia.
Necessity: A study on chronic pain in persons with Down syndrome is clinical relevant for 5 reasons: 1. The neuropathology of Down syndrome without and with dementia affects pain-related gray and white matter, which may alter pain experience; 2. The…
The hypothesis is: Using a multifaceted strategy, the implementation of recommandations will be more succesfull than by using a single strategy. The implemented recommandations will prevent hand eczema among health care workers.
The aim of this study is to elucidate the question whether historic HBV viral load (in samples taken from 1989 – 1996 during pregnancy) is associated with the risk of HBVrelated cirrhosis or mortality in a cohort of non-Asian individuals with…
We hypothesize that addition of low-dose haloperidol prophylaxis (1.0mg twice-daily) on top of the existing standard of care reduces in-hospital delirium incidence, severity and duration in a general patient population, age 70 years or over, who are…
The aim of this study is to provide evidence based dosing guidelines for vincristine in combination with azoles. Therefore we will study the pharmacokinetics of vincristine with and without concomitant azole therapy in pediatric patients with acute…
It is safe to withhold intravenous broad-spectrum antibiotics in low-risk pediatric cancer patients and to shorten antibiotic treatment in a subgroup of medium-risk pediatric cancer patients presenting with febrile neutropenia.
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
A levonorgestrel releasing intrauterine system (LNG-IUS) and endometrial ablation are two frequently used methods for the treatment of menorrhagia, of which the first can be applied by a general practitioner or a gynaecologist, whereas the second is…
Based on current literature we hypothesize that mindfulness based stress reduction training reduces psychological distress and improves 'positive mental health' in medical interns. Possibly MBSR can prevent psychological distress in the…
1. Describe concomittant electrical activation of endocardial and epicardial layers of atrium that have been shown in animal models to be dissociated, and to be involved in the perpetuation of AF; 2. Describe with a density mapping catheter the…
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
Does heated oxaliplatin reduce the acute peripheral neuropathy complaints in patient with a colorectal carcinoma.
1. Currently, there are a wide variety of therapeutic techniques for specific patients and certain psychological problems. The guidelines on mental health care focus only on the specific therapy factors. In addition to these specific therapy factors…