311 resultaten
In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
Electrical stimulation on the foot and lower leg will increase the blood flow and thereby the amount of oxygen to the skin. Our overall hypothesis is that this will help to reduce the risk of decubitus on the heel. The specific hypothesis for this…
Fluorescent near-infrared imaging can accurately detect pancreatic cancer non-invasively during a whipple procedure.
To evaluate the usefulness of the VascuLuminator in children that are obtaining a venous cannulation prior to elective non-cardiac surgery.
A randomized controlled trial to compare the following strategies: two IVM-ICSI cycles or one COH-IVF/ICSI cycle. These strategies are expected to have comparable outcomes for ongoing pregnancy rates and direct costs (treatment costs). IVM is…
High-risk human papillomavirus (hr-HPV) DNA testing complementary to current cytology examination (i.e. Pap test) of cervical smears has shown an increased sensitivity and negative predictive value (NPV) for cervical cancer and its precursor lesions…
ARA290 will reduce disease activity in rheumatoid arthritis.
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Regular exercise has been recommended for diabetes patients for many years, and has been identified along with diet and insulin as one of the three components of good therapy. From a physiological perspective, structured exercise interventions have…
Stress vulnerability as reflected by cortisolreceptor gene polymorphisms, influences course of bipolar disorder defined by number of episodes, physical health and cognitive functioning.
the aim of this study is to compare two strategies that present a large contrast in the stimulation dosage, i.e. a high dosage of stimulation versus a low dosage of stimulation. Our study is designed to objectively compare the ongoing pregnancy rate…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
1. To determine the reproducibility and sensitivity of the Energy Cost of Walking test (ECWT) in boys with Duchenne muscular dystrophy, in comparison with the reproducibility and sensitivity of the 6-Minute Walk Test (6MWT); 2. To evaluate the 1-…
A postoperative retransfusion system is most effective in terms of allogeneic blood transfusion rates when in situ for maximum of 6 hours after major orthopaedic surgery.
In general practices, proactive care for potentially frail older people with the use of Utrecht Periodic Risk Identification and Monitoring (UPRIM) and the use of a Geriatric Nurse Primary Care (GNPC) will result in better daily functioning in…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Our primary objective is to compare the short term (3 months) clinical and radiographic results of the Bledsoe Thruster with the SofTec OA Brace in the management of patients with medial knee OA and a varus leg alignment.
To validate the hypothesis by Sampson on retrograde menstruation by using modern imaging modalities.