218 resultaten
A nutrient dense infant formula promotes growth more effectively than current practice.
AAA is a common disease and a major cause of death due to rupture. Preventive surgical aneurysm repair is costly and associated with considerable morbidity and mortality. Doxycycline has been shown to attenuate the expansion of aneurysm in animal…
Intravenous ketamine infusion will result in analgesia
1. Childhood cancer patients who follow the QLIM intervention program will: a. achieve significantly higher levels of physical fitness after the 12 week intervention compared to patients in the control group, as assessed by objective performance…
The null hypothesis of this research is that the ZCQ outcome of PDI surgery is similar to the ZCQ outcome os surgical decompression at 1 year after surgery.
Computerized decision support (CDSS) for tailoring prevention to the local circumstances using the guidelines of the Dutch college of general practitioners has impact on preventive activities in the primary care setting
The MOT test will be able to detect malaria parasites based on malarial pigment in a finger prick blood sample in less that a minute.
Compare the overall safety profile in both arms : Assess the impact of differences in toxicity profiles on the incidence of dose reduction or dose delay due to grade III-IV toxicities during treatment of patients with pre-treated metastatic breast…
We postulate that: a. Patients with stable asthma have increased presence of viruses and bacteria in the airways as compared to controls. b. Severe asthmatic patients have a higher load of viruses and bacteria than mild asthmatic patients. c.…
We hypothesize that after 12 weeks treatment with infliximab 75 % of the patients will reach a PASI75, whereas after treatment with etarnacept 50% will reach a PASI75.
Muscle hypoxia, either chronic or intermittent (exercise-induced), is responsible for the altered muscle oxidative phenotype in chronic obstructive pulmonary disease and chronic heart failure through modulation of the regulatory molecules PGC-1/…
Addittional training of teachers will result in greater effect-sizes for a school-based child intervention program for childhood behavior problems. Assessment of stepped-care child, teacher and parent intervention.
A first hypothesis is that an advanced quality improvement program (AQIP) significantly improves clinical outcomes in persons with type 2 diabetes compared to a usual quality improvement program (UQIP). The second hypothesis is that persons with…
We hypothesise that the Taperloc BoneMaster coated stem is equal or better than conventional porous coated or cemented stem focussing on implant ingrowth and bone remodelling.
An intensive rectal wash-out program for constipated girls with NNBSD is as effective in curing recurrent urinary tract infections as cognitive bladder training in standard outpatient treatment.
Gonadotropins after 5-7 ovulatory cycles with CC will lead to more multiple gestations and higher costs compared with extended CC treatment. Combination of CC or gonadotropins with IUI may result in a higher pregnancy rate.
Aspirin (acetylsalicylic acid) is the cornerstone of primary and secondary cardiovascular disease prevention, but its preventive effects are reduced in the presence of diabetes mellitus. Whether hyperglycaemia plays an important role in the reduced…
Combination of biatrial pacing and class III anti-arhythmic drug Sotalol will significantly reduce incidence, frequency and duration of postoperative atrial fibrillation.
Determine whether AN-PEP enzyme is effective in mitigating the effects of 8 g wheat protein ingestion in patients with celiac disease
Therapeutic effect of bosentan in patients with Behçet's disease due to antiinflammatory effects on the vascular wall.