2244 resultaten
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
Theoretically there are many advantages of using the Fixion ® IM Humeral nail, like a significant reduced surgical and fluoroscopic exposure time. The procedure is simple and minimal invasive. No interlocking screws are needed, thus there is a…
The guided internet-based behavioral activation intervention is expected to show favorable effects in comparison to online-delivered minimal psychoeducation without support in participants with depressive disorders, as shown by the results on…
The intervention will result in: - higher observed sensitivity and more positive attitudes towards sensitive caregiving in professional caregivers - lower cortisol levels, higher wellbeing and more attachment security in infants - less separation…
An activity stimulation program improves mobility performance and fitness in children with cerebral palsy.
We aim to study the use of braces for thoracolumbar burstfractures, not only by measuring the functional scores and the effect of the bracing or functional treatment on the increase in kyphosis angle, but also on (health related) quality of life and…
Multiple rounds of S(+)-ketamine infusions will give more profound and prolonged pain relief compared to a single infusion of S(+)-ketamine.
1. A multidimensional lifestyle intervention, including aspects of increased awareness, motivation, self-management, diet, exercise, and a supportive environment, improves or prevents deterioration of the cardiometabolic risk factors of SMI…
It is important that parents quit smoking, as this has serious detrimental effects on their own health and their children's health. The majority of parents want to quit smoking. However, many quit attemts are unsuccessful. Recently a proactive…
A 16-week multidisciplinary lifestyle program, based on (1) a WFPD, (2) exercise and (3) stress management H0: has no effect on the WOMAC in patients with hip- and/or knee osteoarthritis and metabolic syndrome, in comparison with usual care. H1:…
Perturbation-based gait training improves dynamic stability and reactive responses in daily life in older adults. Therefore, the risk of falling can be reduce by training.
In the Netherlands, case managers play an essential role in the care chain for people with dementia living in the community. Because the profession has just been started, there is a lack of evidence-based practice to provide treatment for agitation…
We expect that parents involved in the program (as compared to controls) will be more involved in high qualitative communication on alcohol topics, have more confidence in discussing alcohol matters and greater efficacy to prevent their children…
Compression therapy is not necessary after VNUS. Patients receiving no compression therapy after VNUS will have similar outcomes in post-operative pain, oedema, and HRQOL, post-operative complications, time to full recovery.
Custom made orthotic insoles by a podiatrist are (cost)effective in reducing pain and improving function in patients with plantar fasciitis compared to sham orthotic insoles and education alone.
Simular outcomes in patients with 4 implants compared with patients with 6 implants with respects to peri-implant bone level stability
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
The NTX intervention training leads to significant increase in both near and far transfer outcomes, in comparison with the effects of a training of an active control group.
We hypothesize that an initial CPAP level of 15 cmH2O followed by down titration to 8 cmH2O is better CPAP strategy for preterm infants at birth when compared to the currently used initial CPAP level of 5 cmH2O followed by up-titration to 8 cmH2O…
We want to test the hypothesis that internet based guided self-help is not more expensive and not less effective than usual care for patients with phobias.