251 resultaten
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
A. Rocuronium will induce impairment of carotid body function through blockade of cholinergic neurotransmission in carotid bodies resulting in a reduced or absent ventilatory response to isocapnic hypoxia. B. Sugammadex will completely restore…
The overall hypothesis is that balance-specific exercise training only improves postural control of sway measured in standing and causes retention of the improved sway behavior and that such behavioral improvements correlate with changes in measures…
The study will assess drug-induced change in performance in divergent thinking and goal-directed behaviour when comparing psilocybin to placebo, before and after an induction of stress. Additional study parameters include frontal-subcortical…
Faecal transplantation from a healthy donor can restore the dysbiosis present in adolescents with refractory IBS, thereby inducing improvement of the IBS complaints.
Eosinophils play an important role in the inflammatory processes in the lung of asthmatic patients. Mepolizumab inhibits homing of these cells. The hypothesis is tested that mepolizumab affects the kinetics of these cells in blood and sputum.
The hypothesis is that receiving additional counselling will lead to greater improvements in behaviour change compared to no additional counselling.
•To investigate the safety and tolerability of multiple ascending oral doses of DNL104 in healthy subjects •To characterize the pharmacokinetics (PK) of DNL104 in plasma and measure the trough concentrations of DNL104 in CSF. •To Explore the…
We hypothesize that liraglutide treatment, initiated before cardiac surgery, is effective in lowering the number of patients needing perioperative insulin adjustments and reducing the total amount of insulin needed in the perioperative period when…
Common colds have a significant impact on individuals, health care and economy. Functional food ingredients can reduce incidence, duration and severity of common respiratory tract infections in healthy elderly and adults. We hypothesize that test…
Tranexamic acid reduces the necessity for surgery and increases quality of life.
We hypothesize that tACS can enhance brain synchronization between frontal and parietal regions, thereby improving cognitive functioning in MS patients.
The two primary objectives of this study are: 1. To increase therapeutic effectiveness of an eye movement desentization and reprocessing (EMDR) treatment session in patients with post-traumatic stress disorder (PTSD) by reactivating the updated…
Regular milk consumption will improve height and weight development , and blood micronutrient status
The aim of the study is to investigate whether a verbal suggestion concerning the relaxation exercises alone or in combination with actually performing relaxation exercises can alter self-reported stress and psychophysiological measurements of…
Primary: Adding a brief mild psychosocial stressor immediately prior to an experimental analogue traumatic event (the frequently used and well-validated trauma film paradigm) will increase the ecological validity of the analogue traumatic event, by…
The primary objective is to investigate whether exogenous oxytocin administration enhances the placebo effect of classical conditioning and verbal suggestions as measured by subjective pain intensity to a previously validated heat pain conditioning…
The hypothesis is that repeated remote ischaemic postconditioning (by improving vascular, immune and anti-inflammatory pathways) will minimize infarct size and, subsequently, will improve clinical outcome in stroke patients.