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Association of BMI with COVID-19 incidence and severity

High BMI is associated with worst prognosis after SARS-CoV2 infection

Promoting informed decision making about maternal pertussis vaccination among pregnant women

A 10% point difference between the experimental groups and control group in MPV uptake is expected.

Effect of oral Curcumin on Gut Microbiota Composition in patients with Diabetes Type II, Ulcerative Colitis, Crohn's disease and healthy subjects

Curcumin is expected to have a positive effect in the composition of gut microbiota and the measurable outcomes of this change in composition.

The relation between post-stroke depression and insomnia

Severity of insomnia at three months post-stroke is correlated with severity levels of post-stroke depression.

A multicenter randomized controlled trial assessing and comparing long-term scar quality after micrografting versus mesh grafting of deep dermal burns

Our hypothesis is that treatment with micrografting, when compared to conventional meshed graft, will result in a better scar quality and smaller donor site size.

The association between a drop in systolic blood pressure from the individual reference value and in-hospital mortality in ED patients.

A low delta SBP is associated with an increased risk of mortality

Effect of TLC-VR training on patient anxiety during sedation for colonoscopy

A therapeutic language and communication training using VR helps OR-staff to diminish patients anxiety levels before going into surgery.

Hearing preservation in cochlear implantation surgery

Combination of a round window insertion approach and a lateral wall electrode array minimizes insertion trauma

Development of a more SensItive method to predict Breast cancer recurrence after 5-Years of endocrine treatment making use of diagnostic LeukApheresis to detect circulating tumor cells

We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…

A prospective Study on prevalence and determinants of Ototoxicity dUring treatmeNt of childhooD cancer

We will identify clinical and cancer treatment related risk factors associated with hearing loss, tinnitus and vertigo. We will determine the prevalence of hearing loss, tinnitus and vertigo in a prospective cohort of CNS/ solid tumor patients.

The effects of Apps on Mental and Physical wellbeing (AMP)

Research Question 1: Do mental health apps improve mental wellbeing? This question will be investigated by testing the following hypothesis: There will be an interaction between condition (allocation to one of the 4 apps vs. no-app control; between…

Specificity of the effects of parenting program components to reduce risk factors for child conduct problems

We will test whether each component specifically reduces the risk factor it aims to target: Does component A (relational perspective based child-led play) improve the parent-child relationship, and not coercive parent-child interaction cycles or…

Biomarkers for prognosis in critically ill COVID-19 patients : a prospective cohort study

Biomarkers like MR-proADM and CT-proAVP predict severity and outcome in critically ill COVID-19 patients. MR-proADM and CT-proAVP at admittance can be higher in non-survivors and biomarker clearance over the days will be higher in survivors.

Modifications in implant features in the TFNA proximal femoral nail as successor of a more conventional intramedullary nail were associated with an increase in fixation failure rate.

No improvement of fixation failure will be found after the introduction of the TFNA

Hormonale (dys)functie in clusterhoofdpijn

Het aantonen van verschillen in geslachtshormonen tussen mannelijke clusterhoofdpijnpatienten en mannelijke controles

Identificatie en karakterisating van niet-alcoholische vette leverziekte in eerstelijnszorg.

De primaire doelstelling van deze cohortstudie is het bepalen van de prevalentie van eenvoudige en gevorderde NAFLD bij risicopersonen die door de huisarts worden gevolgd De secundaire doelstellingen zijn:1. Het bestuderen van de factoren gelinkt…

Landelijke studie naar de aanwezigheid van en het risico op medische en psychosociale gevolgen van kanker bij adolescenten en jongvolwassenen: De COMPRAYA studie

Het doel van deze studie is inzicht krijgen in de prevalentie, risicofactoren en mechanismen van verminderde gezondheidsuitkomsten (medische en pyschosociale, korte en lange termijn effecten, als ook de late effecten) over tijd bij AYA-…

Versla de pijn in sikkelcelziekte

Het doel van deze proof- of- concept studie is om d.m.v. hartslag gerelateerde metingen via een Apple Watch:- A. Acute Chest Syndroom te voorspellen in patiënten met sikkelcelziekte die liggen opgenomen in het ziekenhuis i.v.m. een pijnlijke crisis…