Physiotherapy will diminish the development , extent and duration of motor problems in children with acute lymphoblastic leukaemia.
Bron
Verkorte titel
Aandoening
Acute lymphoblastic leukaemia.
Ondersteuning
Onderzoeksproduct en/of interventie
Geen registraties gevonden.
Uitkomstmaten
Primaire uitkomstmaten
Motor performance is measured with the Motor Assessment Battery for Children - a standardised test for motor performance - at the onset of chemotherapy, after six weeks, one year after starting chemotherapy and on completion of therapy.
Achtergrond van het onderzoek
Children diagnosed with acute lymphoblastic leukaemia are randomised to a physiotherapy (PT) group or to a control group.
Children who are randomised to the PT group receive a standardised exercise program, which starts in week 1 of their chemotherapy treatment, is carried out at home and monitered by a physiotherapist.
Children who are randomised to the control group, only receive physiotherapy if motor problems occur.
This is current standard practice. Motor performance of the children is measured at the onset of chemotherapy, after six weeks, one year after starting chemotherapy, on completion of chemotherapy.
Objective signs of polyneuropathy, i.e. decreased reflexes, sensory disturbance and muscle weakness are assessed.
The assessor is kept blind to the group to which the children are randomised.
Doel van het onderzoek
Physiotherapy will diminish the development , extent and duration of motor problems in children with acute lymphoblastic leukaemia.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Children who are randomised to the physiotherapy group receive a standardised exercise program, which starts in week 1 of their chemotherapy treatment, is carried out at home and monitored by a physiotherapist.
Children who are randomised to the control group, only receive physiotherapy if motor problems occur. This is current standard practice.
Publiek
P.O. Box 2060
Annelies Hartman
Amsterdam 3000 CB
The Netherlands
j.hartman@erasmusmc.nl
Wetenschappelijk
P.O. Box 2060
Annelies Hartman
Amsterdam 3000 CB
The Netherlands
j.hartman@erasmusmc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Children, aged 1-18 years diagnosed with acute lymphoblastic leukaemia.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Additional medical conditions known to have an effect on motor development;
2. Cognitive impairment.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL213 |
NTR-old | NTR251 |
Ander register | : N/A |
ISRCTN | ISRCTN63483122 |