It is hypothesized that persons with MS have a higher energetic cost of walking due to more variability in gait parameters.
Bron
Verkorte titel
Aandoening
Multiple Sclerosis
Ondersteuning
Onderzoeksproduct en/of interventie
Geen registraties gevonden.
Uitkomstmaten
Primaire uitkomstmaten
Walking fatigability
Achtergrond van het onderzoek
Walking capacity is reported as one of the most important bodily functions for maintaining a high quality of life in persons with Multiple Sclerosis (pwMS). It has been shown that limitations in walking capacity in pwMS are related to fatigue, which subsequently leads to a decreased daily physical activity. This may impact physical fitness and ultimately lead to a decreased social role participation. However, it is not well known whether this limitation in walking capacity, measured during walking is related to less energy efficient walking and thus a poor walking economy. It is proposed that assessing the relation between a decline in walking capacity (walking fatigability), walking economy and walking characteristics (e.g. spatiotemporal parameters, kinematic and kinetic profiles, muscle coordination patterns) can lead to a better understanding of the determinants of walking fatigue in pwMS. In addition, exploring its impact on daily activities and social participation will aid rehabilitation of pwMS .
Doel van het onderzoek
It is hypothesized that persons with MS have a higher energetic cost of walking due to more variability in gait parameters.
Onderzoeksopzet
1
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Diagnosed MS by neurologist
- Expanded Disability Status Scale 1- 5.5
- Able to walk without walking aid and orthoses
- Age between 18-65 years
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Recent (3months) relapse
- Recent (12 months) arthroplasty or fracture
- Comorbidities affecting functioning (such as diabetes mellitus, malignancies)
- Contra-indication for physical activity or exertion tests
- Botulinum treatment in lower extremity <6 months before measurement
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiƫnten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
Register | ID |
---|---|
NTR-new | NL7921 |
CCMO | NL67805.068.18 |