Time-lapse monitoring in IVF and ICSI patients

The SelecTIMO study is a multicenter, three-armed, randomized, controlled,

double blind trial. It will establish whether the use of time-lapse monitoring

for embryo culture and embryo selection can outperform routine

morphological embryo culture and selection. Furthermore, this trial will reveal

whether an improvement of the clinical outcome is mediated through the

stable culture environment and/or optimized selection method using Eeva

time-lapse Results.

Embryo selection using the Geri+ time-lapse system in combination with the

Eeva Test (Early Embryo Viability Assessment) will increase the (cumulative)

ongoing pregnancy rate of IVF and ICSI patients and thereby balance

additional costs of TLM (time-lapse monitoring) equipment.

N/A

A) Embryo selection based on Eeva Results and continuous culture in Geri+

incubator (Geri+Eeva complete) and B) Routine embryo selection based on

morphology and continuous culture in Geri+ incubator (Geri culture only) will

be compared to C) Routine embryo selection based on morphology and

interrupted culture in Geri+ incubator (Control). Embryos in all three groups

will be cultured in the Geri+ time-lapse incubator.