We presume that reducing the fasting period by adding a carbohydrate drink 2-3 hours prior to surgery is a good and feasible option to decrease orthostatic intolerance and -hypotension. Moreover, the pre- and postoperative well-being is thought to…
Verkorte titel
Health condition
Knee osteoarthritis
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
- Orthostatic intolerance and -hypotension during first postoperative mobilization.
Achtergrond van het onderzoek
During the last decades, fast-track protocols have been implemented to improve the postoperative outcome and to reduce the lenght of hospital stay after Total Knee Arthroplasty (TKA). One of the interventions of fast-track protocols is early mobilization. This can be compromised by orthostatic intolerance and -hypotension due to various causes including prolonged fasting. Moreover, preoperative fasting is stressful for patients.
Reduced preoperative fasting was not associated with increased intake related complications. To further optimize fast-track rehabilitation it is assumed to reduce the preoperative fasting period to prevent issues during early mobilisation.
Doel van het onderzoek
We presume that reducing the fasting period by adding a carbohydrate drink 2-3 hours prior to surgery is a good and feasible option to decrease orthostatic intolerance and -hypotension. Moreover, the pre- and postoperative well-being is thought to be improved and thereby the overall TKA rehabilitation.
Onderzoeksopzet
Verwachte start inclusie november 2019
Verwachte volledige inclusie december 2021
Onderzoeksproduct en/of interventie
The intervention group will receive a carbohydrate drink 2-3 hours prior to surgery
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
All patients, 18 years or older, with primary or secondary osteoarthritis of the knee who qualify for a unilateral primary total knee arthroplasty.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Patients with risk factors for reduced fasting (metabolic disorders (Diabetes Mellitus), age >80 years);
- Insufficient command of Dutch;
- ASA >3;
- Patient who are incompetent to decide.
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL7996 |
| Ander register | METC-LDD : Z19.025 |