Is 'inference-based approach', een nieuwe psychotherapeutische behandeling voor patiënten met een obsessieve compulsieve stoornis met gering inzicht, effectiever dan een behandeling met cognitieve gedragstherapie? Een gerandomiseerd gecontroleerd onderzoek.

The aim of this project is to improve treatment options for OCD patients with poor insight (overvalued ideation). It studies whether Inference-Based Approach (IBA), a new form of psychotherapy that was specially developed for this subgroup of OCD patients, is more effective than Cognitive Behavioral Therapy (CBT). A recent cognitive model of OCD, the inferential confusion model, provides an explanation of poor insight. In addition, O'Connor and colleagues demonstrated in 2005 in Canada that IBA, which is based on the inferential confusion model, showed a greater clinical improvement for patients with OCD and poor insight.

In this RCT, 80- patients with OCD and poor insight, recruited at the outpatient clinica of GGZ inGeest and GGZ Meerkanten will be randomised over IBA and CBT.
IBA is a new form of cognitive therapy which purposes to resolve obsessions by means of enhancing reality testing.
Patients with a primary diagnosis of OCD with poor insight are enrolled in the study.
Timepoints are basline and posttest, after 24 weeks of treatment.
The study will provide an answer to the question whether IBA is a useful treatment for OCD patients with high levels of poor insight.

In a sample of patients with obsessive compulsive disorder (OCD) with poor insight, treatment with 'inference-based approach' (IBA) is superior to cognitive behavioral therapy in decreasing OCD symptom severity.

Baseline and posttest, after 24 weeks of treatment.

Inference-based approach (IBA): This treatment points mainly to enhancing reality testing. The purpose is to resolve obsessions by enabling the patient to better differentiate between actual situations as they can perceive by using their senses, versus imaginary situations.


Control condition: Cognitive behavioral therapy.