To enhance insight on the coding of sensory stimuli by signal analyses
ID
Bron
Verkorte titel
Aandoening
Patients with epilepsy (intracranial registration)
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
To study the patterns and topographical distribution of the electrical signal generated in cortical neurons during the processing of sensory stimuli (of which the nature will depend on the primary function of the cortical area under investigation) in epileptic patients under intracranial registration.
Doel van het onderzoek
To enhance insight on the coding of sensory stimuli by signal analyses
Onderzoeksopzet
7T fMRI scan (presurgical) and postoperative test. No other timepoints.
Onderzoeksproduct en/of interventie
No interventions are planned
Algemeen / deelnemers
Wetenschappers
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
• Medically refractory epilepsy
• Diagnostic workup up till that moment has not led to decline the patient for resective epilepsy surgery
• A suspected (neo-)cortical seizure focus at the surface of the brain
• Planned implantation of intracranial electrodes
• Incapacitating epilepsy or seizures
• Minimum age 18 years
Inclusion criteria for healthy control:
• Voluntary controls will be selected based on the gender and age distribution of the patients programmed for grid implantation surgery.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
• Patients with (co-existent) psychogenic, non-epileptic attacks, or low IQ (below 70).
• (post-ictal) psychosis during the registration period will lead to exclusion from the study.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4483 |
| NTR-old | NTR4616 |
| Ander register | : iEEGstudy |