123 results
Primary: To identify potential diagnostic cytokine profiles for an allergic reaction towards a dental device in patients with symptoms of oral metal allergy. Which might lead to a better understanding of allergic based systemic reaction of oral…
To collect prospective clinical and molecular data on the phenotypical characteristics of patients with atopic dermatitis (AD) receiving standard care targeted systemic treatment.
Primary Objective:Our main objective is to analyse if the microbiota composition of the affected skin is different from the non-affected skin in XRI and ARCI. Secondary Objectives:(1) To investigate the composition of the skin microbiota of patients…
Objective: The main objective of our study is to examine whether we can use the IT (as determined by visual irritation grading scale after SLS patch test) to predict HS formation after reduction mammaplasties. The secondary objectives consist of…
The primary objective will be to evaluate the sensation of the keloids as measured by Semmes-Weinstein monofilaments (SWM), Pressure Specified Sensory Device (PSSD) and/or Quantitative Sensory Testing (QST), compared between patients with and…
(I) To compare patient friendliness in adult psoriasis patients between two non-invasive cytokine detection methods: TAP and TAPE. (II) To assess the correlation in cytokine detection by TAP and TAPE stratum corneum sampling in psoriasis patients.
The aim of this study is to measure the lymphflow in the superficial lymphvessels in the dorsal forearm in patients with no history of lymphedema. In order to further study lymphedema and to improve the technique of lymphaticovenous anastomoses, it…
The main aim of this project is to obtain a better control and treatment of immune-mediated diseases by exploring the universe of microenvironment imposed tissue signatures and their correlates in liquid biopsies.
The aim of this study is to improve our understanding of clinical, virological, and psychosocial outcomes in patients with MPXVID. To get a better understanding of associated risk factors for MPXV infection, and to measure quality of life and stigma…
Primary objectives:To evaluate the pathogen host interactions between S. aureus and NS patients:o IgG and IgG4 responses against S. aureus antigens in NS patients will be compared with IgG and IgG4 responses against antigens of other bacteria (e.g.…
Our primary objective is to assess the relation between itch and sustained attention in 7-11 year old children with atopic dermatitis (AD). Secondary objectives are to assess the relation between itch and task-oriented behavior, to assess whether…
Given the worldwide-observed rapid increase in the prevalence of allergic diseases, it is likely that environmental risk factors, including geographic area and lifestyle factors play a substantial role in the development of allergies and other…
To determine which biological processes play an essential role in immune-pathological changes in vitiligo skin depigmentation.
The main objective of this study is to evaluate the effect of anti-fibrotic/anti-SSc therapies using a SSc organ-on-a-chip (OoC) model. The secondary objectives of the study are:- To engineer an advanced OoC device to model SSc that incorporates key…
Our primary objectives are to analyse the gene expression profile of non-lesional and lesional skin of patients with NS (ichthyosis linearis circumflexa (ILC) phenotype and scaly erythroderma (SE) phenotype) using single cell RNA sequencing and…
This study has been transitioned to CTIS with ID 2024-513534-38-00 check the CTIS register for the current data. Investigate whether treatment with azithromycin has an inhibitory effect on the mTOR pathway and/or C. acnes, causing a reduction of the…
The main parameter of this study is the objective quantification of the biomechanical properties of skin and keloid/hypertrophic scars, as compared to the golden standard (Cutometer).The discriminating capacity will be tested by comparing healthy…
In this proposal, we therefore aim to characterize in detail the cutaneous B cell response in patients with isolated CLE (CLE only) and patients with systemic and cutaneous disease (SLE/CLE). Primary Objectives: 1. Characterize autoreactive B cells…
1. To identify immunological alterations in peripheral lymphoid/skin/synovial tissue of patients with psoriatic artritis and psoriasis2. To correlate these alterations with disease stage, prognosis, treatment response3. To compare immunological…
To identify clinical and immunological parameters that predict the course of disease of non-tuberculous mycobacterial skin and soft tissue infections.