8962 results
To investigate associations between IBD severity, ASCA titer, microbiota composition and C. albicans strains present in feces.
Primary Objective: -To explore the percentage of positive total PEth levels in blood, as a proxy of alcohol consumption, in pregnant women during their first visit to the obstetrics department.Secondary Objectives: To explore the distribution of…
Primary Objective: 1. Determine if assessment of mucosal and serological immunological characteristics in combination with clinical indicators of disease behaviour and response to therapy can identify immune-based phenotypes with implications for…
To assess whether nutritional status can affect the outcome of spatial cognition training in the brain.
The aim of the proposed study is to obtain insight into the needs, functioning and quality of life and changes in these outcomes of people with severe MS who are treated in NU and to identify the experiences, facilitators and barriers using the…
To study the efficacy of danazol in patients with pulmonary fibrosis, and to investigate what factors are associated with effective treatment.
To evaluate the feasibility of the study after 20 weeks of follow-up, which includes the evaluation of the dose-reduction algorithm in tocilizumab-treated patients with RA.
The primary objective of this study is to evaluate the effectiveness of lipofilling in treatment of speech and swallowing impairment after treatment for head and neck cancer. The secondary objective is to evaluate the effect of lipofilling on tongue…
Primary Objective: 1. To determine whether there is a difference in arterial wall inflammation between well-controlled and poorly-controlled type 1 diabetes patients2. To determine whether patients with type 1 diabetes have a higher level of…
With this study we will evaluate the following hypothesis: Does acute systemic inflammation induces plaque instability and could it be repsonsible for the elevated risk of cardiovascular events. Eventually this study can contribute to the knowledge…
The study aims to answer the following research questions:1. How high/low are levels of symptomatology of depression and/or PTSD in traumatised refugee children in ASC?2. Do symptom levels decrease after a short-term trauma-focused intervention?3.…
The main objective of this study is to assess the prevalence cardiovascular disease and the prevalence of risk factors for cardiovascular disease in patients with gout, and to quantify the risk for cardiovascular disease in patients with gout. The…
To gain further insight into the interaction and possibly shared pathophysiological mechanisms of female-specific cardiovascular risk factors and events we will quantify white matter hyperintensities on brain MRI and assess endothelial function in…
To study sensory processing and hyperexcitability in children with ASD and epilepsy using neurophysiological measurements (EEG/ERP).
Does humoral and/or cellular rejection play a role in recurrent miscarriage of unknown etiology?Can biomarkers of humoral and/or cellular rejection be used for the detection of patients who are likely to suffer a miscarriage in a next pregnancy?
The aim of the project is to examine the association between clinical, environmental and genetic characteristics of the recipient of erythrocyte transfusions and the risk or resistance to immunization against erythrocyte alloantigens that he/she was…
To assess the number of patients in remission, 12 months after dose adjustment of IFX from 5mg/kg to 3 mg/kg. Secondary objectives include: number of relapses, defined by increase of fecal calprotectin and/or CRP and clinical activity, subsequently…
The aim of this project is to evaluate the clinical value of biomarkers in adult patients with congenital heart disease, in particular:1) quantify biomarkers of neurohormonal activity as NTproBNP, endotheline-1 and of immunological activity as CRP,…
This study aims to enhance pharmacotherapeutic effects in patients with recent-onset RA by means of conditioning (via a variable reinforcement schedule).
Circulating CriPec docetaxel nanoparticles are designed to be in a higher degree than the original compound (docetaxel) to be trapped in tumor tissue due to the enhanced penetration and retention (EPR) effect. Subsequent release of docetaxel from…