588 results
The goal of the current observational multicenter pilot study is to investigate if an 8-week Acceptance and Commitment group therapy for youth with ASD is an effective intervention to increase adaptive emotion regulation, psychological flexibility…
The primary objective is to determine the incidence and severity of sicca complaints after ICI administration. The secondary objectives are: 1) to measure changes in objective measures of oral and ocular dryness after ICI administration; 2) to…
Our main objective is to conduct a pilot study testing the applicability and face/external validity of the battery in a young-onset PD cohort, alongside age-matched healthy controls. We aim to gain deeper insights into the complex interrelationships…
The aim of this randomized trial is to appraise the impact of IABP in the treatment of early stages of cardiogenic shock, irrespective of etiology. Findings of this randomized trial may enhance clinical decision making regarding the use of MCS in…
To introduce human biomonitoring as a novel approach to study both exposure and as early indicators of effects related to the use of chemicals in hospital-based healthcare. This is expected to increase awareness and better understanding of how work…
In the Netherlands, TEE is currently not used in emergency departments during cardiac arrest. The purpose of this study is to investigate if point-of-care TEE can be used effectively and safely in patients with cardiac arrest.
The main objective is to determine genetic phenotype and the prevalence of anti-HLA (human leucocyte antigen) and anti-HPA (human platelet antigen) antibodies in patients with Glanzmann thrombasthenia.
Primary: To determine the efficacy and safety of bel-sar compared to sham control for thetreatment of primary indeterminate lesions and small choroidal melanoma (IL/CM).Secondary: To assess the systemic pharmacokinetics (PK) and immunogenicity of…
Identifying placental disease during pregnancy using cfDNA of placental cells in the maternal circulation to discover new therapeutic placental targets for fetal treatment.
To investigate the frequency of V*9Vδ2-T cells in patients with metastatic castration-resistant prostate cancer
To determine the targets for an intervention aimed at reducing revictimization after trauma-treatment by means of a co-creation session. A secondary objective is to gain insight into the interpersonal revictimization history of people currently in…
The primary objective is to assess the ability to achieve preoperatively planned resection volumes by adding EM tracked navigation in RAPN, as minimizing the removal of healthy kidney tissue is challenging nowadays. A deviation within 35% between…
The primary objective of this study is to investigate the effect of the implementation of the KDIGO bundle in patients at high risk for AKI after major surgery as compared to standard of care.
To investigate the effect of distracted consumption on glucose variability in women with GDM and to investigate moderating effects of type of distractor and perceived stress.
To investigate the effect of a daily sachet of probiotics for 12 weeks vs placebo on vitamin K status in renal transplant recipients.
Primary objective: To determine the characteristics of language, speech and motor functions in MCI due to AD, mild AD and moderate AD Secondary objective: To explore the association between language, speech and motor functions in MCI due to AD and…
To establish the performance of the idi-CGM system among persons with DM.
The main objective is to asses functional anatomical restoration of the linea alba through functioning in mean peak torque, and ultrasound examination.
Primary: To determine the efficacy and safety of bel-sar compared to sham control for thetreatment of primary indeterminate lesions and small choroidal melanoma (IL/CM).Secondary: To assess the systemic pharmacokinetics (PK) and immunogenicity of…
Primary objective: To assess the effect of passive heat acclimation, in combination with low-to-moderate intensity exercise, on cardiovascular and thermophysiological responses in overweight, older individuals.Secondary objective: To assess the…