3710 results
zie protocol
Primary general objectives of the NEO study1. To study the pathways that lead to common diseases in overweight and obese individuals.2. To identify novel determinants of various diseases and conditions in overweight and obese individuals.3. To study…
This study has been transitioned to CTIS with ID 2024-515487-31-00 check the CTIS register for the current data. The primary objective of this study is to describe the pharmacokinetics of antiretroviral agents, for which no or limited available…
We want to investigate the hip joints of young very active male soccer players to gain greater knowledge on the development of cam impingement, concerning the shape deformities, the age of onset and the occurrence of cartilage lesions.
To demonstrate the safety and effectiveness of the Freedom SOLO heart valve when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis. Safety will be determined by survival and complication rates. Echocardiography and…
Assess hepatotoxicity of long-term azathioprine and 6-mercaptopurine use in IBD-patients as compared with a cohort of long-term 6TG users
General objective:To develop or validate a clinical prediction rule for major bleeding in patients on oral anticoagulant therapy (OAT) who have been safely anticoagulated without bleeding or venous thromboembolism (VTE) recurrence for 6 months since…
The objective of the RAAK study is to collect bloed and joint tissue (cartilage, ligaments and subchondral bone) of patients that undergo a total joint replacement due to a endstage OA. Genomic material (DNA and RNA) will be isolated from both the…
The aim of this research project is to study a large a group of patients with tonic dystonia longitudinally, to accurately describe the phenotype, to investigate the potential underlying mechanisms and to identify possible causes and risk factors.
The objective is to assess the effectiveness of exercise therapy (running therapy or Nordic walking) ondepression in adults, in addition to usual care (primary aim) and on metabolic syndrome measures, qualityof life and cost effectiveness (secondary…