338 results
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
Does intensive multifactorial coaching of patients with chronic renal insufficiency by nurse practitioners result in a reduction in cardiovascular events, cardiovascular mortality, all cause mortality and change in decline of renal function.
Patients prefer naratriptan over paracetamol 1000 mg for the acute treatment of migraine attacks.
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The high incidence of cardiovascular disease in patients with end stage renal disease (ESRD) is related with the accumulation of uremic toxins in the middle and large-middle molecular weight range. As online hemodiafiltration (HDF) lowers these…
Patients prefer rizatriptan over ibuprofen for the acute treatment of migraine.
Primary: 1. To compare in inpatients with psychotic depression the antidepressive efficacy at seven weeks of three treatment arms: [1] 7 weeks venlafaxine (maximum dose 375 mg); [2] 7 weeks imipramine (dose adjustment to adequate plasma levels of…
Findings from both epidemiological and basic research point to the possibility that NSAIDS impede the deterioration in schizophrenia.
A post marketing surveillance study to assess safety, clinical performance and survival of the uncemented Glenoid Affinis vitamys Uncemented Glenoid Affinis Vitamys total prosthetic shoulder replacement. All implants already bear the CE-marking.
Primary Objective: To study the effect of different treatment approaches - existing of conservative management, pharmacological treatment and surgical treatment - on sexual function in patients diagnosed with endometriosis. Secondary Objective(s):…
Primary Objective:The study aims to assess freedom from AF ten years after the procedure without the use of antiarrhythmic drugs in patients who underwent thoracoscopic ablation in advanced AF with or without GP ablation. Secondary Objectives:1. To…
To determine the real world response to standard of care CAR T-cell therapy, in order to better understand the intrinsic and extrinsic factors related to treatment success or failure.
To assess the post-operative quality of recovery after robot-assisted as compared to open extended lateral pancreaticojejunostomy.
The primary objective is to assess if consuming a slush puppy combined with glycerol at 0°C can reduce the thermal strain during a three hour march in physically active men compared to an isotonic sports drink at 33°C and a slush drink at 0°C. The…
To evaluate the feasibility, safety and potential efficacy of acupuncture in children with FC. The results of this study will be used to design a future randomized controlled trial (RCT).
The primary objective is to perform a clinical validation of the analytical method for dried blood spot microsampling of cabozantinib, pazopanib, sunitinib, Lenvatinib, nivolumab, ipilimumab, pembrolizumab, atezolizumab or bevacizumab. The secondary…
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
The objective of this project is to test the clinical and cost effectiveness of utilizing the assessment of transdiagnostic dynamics of symptoms to provide a personalized e-health treatment intervention as an automated tool during the waiting list…
The objective of this study is to demonstrate the clinical performance of VENTANA PD-L1 (SP263) CDx Assay in terms of its ability to identify patients with metastatic NSCLC who may benefit from treatment with acasunlimab (GEN1046) in combination…