The primary objective is to assess if consuming a slush puppy combined with glycerol at 0°C can reduce the thermal strain during a three hour march in physically active men compared to an isotonic sports drink at 33°C and a slush drink at 0°C. The…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
n.v.t.
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter is the difference in core temperature between the
following three conditions: isotone sports drink at 33°C (room temperature),
slush puppy at 0°C and slush puppy combined with glycerol at 0°.
Secondary outcome
Secondary study parameters include differences in urine production, heart
rate, sweat production and concentration, blood plasma volume, skin
temperature, peak power and cognitive performance between the conditions.
Additionally, several questionnaires will be conducted during the march to
assess differences in rate of perceived exertion, thermal sensation, thermal
comfort, thirst perception and possible side effects experienced across the
conditions.
Background summary
Military personnel often face high heat stress due to heavy gear and intense
activity, increasing the risk of heat illness. Effective cooling mechanisms,
such as a slush drink, can lower core temperature, while adding glycerol can
help retain fluids. However, to our knowledge, this hasn*t been tested in
military settings before. Therefore, this study aims to determine if the
combined ingestion of a glycerol-slush drink can reduce thermal strain and
improve hydration, potentially enhancing safety and performance in hot
environments in a military relevant protocol.
Study objective
The primary objective is to assess if consuming a slush puppy combined with
glycerol at 0°C can reduce the thermal strain during a three hour march in
physically active men compared to an isotonic sports drink at 33°C and a slush
drink at 0°C.
The secondary objectives are to evaluate the impact on hydration status, sweat
response, and urine production when consuming a slush puppy combined with
glycerol at 0°C, compared to an isotonic sports drink at 33°C and a slush drink
at 0°C, during a three-hour march in physically active men.
Study design
The study uses a crossover design with three different conditions: an isotonic
sports drink at 33°C, a slush drink at 0°C, and a slush drink with added
glycerol at 0°C. Each participant will complete all three conditions in a
randomized order.
Intervention
A three hour march (3 times a 50 minute walk followed by a 10 minute break)
will be performed in a climate chamber set at 33°C with 50% relative humidity.
Each session involves consuming one of the three test drinks 30 minutes before
the march. Several measurements will be taken throughout the march.
Study burden and risks
Participants are required to visit the research site on three separate
occasions for testing. Each visit is expected to last ~4.5 hours, during which
participants will undergo various assessments. Core temperature, skin
temperature and heart rate will be continuously monitored throughout each
visit. Every visit a capillary blood sample (via finger prick) and urine
samples will be collected on five different occasions. At the beginning and end
of each marching block, the participant*s weight will be measured.
Additionally, sweat samples will be collected three times during each visit.
Questionnaires assessing various parameters will be administered throughout the
march at specific timings (3 times per marching block). At the end of the
march, participants will complete a performance and cognitive task to evaluate
their remaining functional capacity.
Participants might experience (small) discomfort related to the finger prick.
Other potential, but monitored risks are the rise of core temperature and
experiencing gastrointestinal discomfort. The participants will be monitored
closely for any adverse reactions during the study. The potential benefits of
this study include a better understanding of strategies to mitigate heat stress
and improve hydration. This has the potential to enhance the performance and
safety of military personnel operating in hot environments in an increasingly
unsafe world.
Kampweg 55
Soesterberg 3769 DE
NL
Kampweg 55
Soesterberg 3769 DE
NL
Listed location countries
Age
Inclusion criteria
A healthy adult male (18-40 years old) who is physically active (at least 2
times per week), and who is able to walk for at least three hours.
Exclusion criteria
• A thermoregulation disorder or a history of heat illness.
• A physical injury that makes the protocol unfeasible.
• A history of- or currently experiencing bowel issues
• Use of medication for cardiovascular conditions, diabetes, and/or medications
that affect thermoregulation.
• Staying abroad (>25 °C) in the past four weeks (to exclude heat-acclimatized
participants).
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL88142.028.24 |