135 results
The primary objective is acquiring insights in the development of BOS in patients after human lung transplantation in an early phase of the disease which can be used to improve immunotherapeutic handling in order to prevent or delay the onset of BOS…
In this study the prevalence and kind of sexual and psychosexual problems will be assessed. Psychological well being is studied as well
We intend to study the role of fronto-striatal circuitry and cognitive control in the inflexible behaviour that is a defining feature of autism.
Objective of this study is to provide evidence for the induction of AGEs in blood and tissue in patients with septic shock.
To obtain insight in the role of the innate immune response, especially Type 1 interferons, in the pathogenesis of RSV LRTI. New techniques are used to unravel the local (nasopharyngeal) immunological milieu during viral LRTI. The hypothesis is that…
Registry is the core study of the European Huntington*s disease Network (EHDN). The aim of the Registry study is to collect prospective data on the phenotypical characteristics of Huntington's disease (HD) mutation carriers regardless of…
To examine cellular damage, intestinal barrier function loss, activation of the Complement system and inflammatory alterations induced by ischemia and reperfusion of the human small and large intestine.Second, we aim to study the consequences of…
The goal of this study is examining the acute effects of insulin on microcirculation in hypertensive insulinresistant subjects and investigate if angiotensine II influences these effects. Amendement: The goal of the amendement is to exame the…
The main aim of this study is to assess the prevalence of allergic and non-allergic health problems in veterinary students in different phases of the veterinary education. On later stage, genetic predisposition for allergies will be studied. In the…
The study objectives are:1. Getting insight into the biological origin of the typical serum protein profile in breast cancer by comparing the protein profiles in breast tissue of benign breast disease patients and primary breast cancer patients with…
The general objective of this study is to elucidate the cellular components for HIV-1 infection in children.
Hypothesis:1. Patients who suffer from a hypopituitarism and an adult-onset growth hormone deficiency (AGHD) express more atherosclerotic disease in the coronary system (compared with a historically formed control subjects, present as a database in…
To determine the frequency of symptoms and signs of a neuromuscular disorder (myopathy, neuropathy) in patients with haemochromatosis. To evaluate in these patients the impact of these symptoms and signs on the quality of life. To assess in patients…
A. To determine prevalence and determinants of impaired glucose regulation 1. To study the prevalence of impaired glucose regulation and type 2 diabetes in the general population aged 40 to 65 years, and to compare these prevalence rates with those…
The purpose of this study is to determine if the development of idiopathic scoliosis is related to neuropathic detrusor/sphincter dyssynergia. When bladder and sphincter function are disturbed, adequate therapy can be started in an early phase to…
Investigate effect of IF on insulin resistance and possible role acylcarinitin profiles and glycolipids
1) To assess whether galactosemia women with ovarian failure are able to produce estradiol after exogenous (normally bioactive) FSH and LH gift 2) To characterize FSH glycan structures
In previous studies we have identified specific receptor and surface protein expression profiles on neutrophils. Some of these profiles point at partially refractory neutrophils. In the current NERTHUS study we have seen that circulating neutrophils…
Is is possible to detect tumorcells in blood in patients with colon cancer with RT-q-PCR.
- To analyze retinoid levels in plasma and amniotic fluid from infants and mothers to establish the potential link between retinoids and CDH. - To establish a registry of blood and tissue samples that will be valuable for future studies of the…