2369 results
To discover human genes which are likely to confer susceptibility for recurrent respiratory papillomatosis
The objective is determine the correlation between the outcome of the cultures of the nasopharyngeal swab, the nose swab, the swab from a handkerchief and the handkerchief.
The main aim of this research is to search for sensitive and specific QEEG markers to differentiate between children with a developmental disorder, in this case ADHD and ASD, and a control group and to differentiate between these two developmental…
The objective of the study is to quantify endurance and respiratory function in subjects with MPS IV A and to better characterize the spectrum of symptoms and biochemical abnormalities in MPS IV A disease over time.
In the present study the prevalence of and risk factors for vitamin D deficiency will be determined in a patient population with a fracture in the upper or lower extremity.
The primary objective of this study is to examine the effectiveness of the serious game called HealSeeker for improving time management, planning and organisation and social behaviour skills of children with ADHD. The secondary objective of this…
This is a phase I/II pediatric dose-ranging study that will evaluate the safety, tolerability and pharmacokinetics of midostaurin in children <18 years of age and >= 3 months who have relapsed or refractory leukemias that may benefit…
• To evaluate the safety of up to 3 additional courses of oral QLT091001 administered once daily for 7 days in subjects with LCA or RP caused by RPE65 or LRAT gene mutations who have been treated previously with a single 7-day course of QLT091001 in…
Primary ObjectiveTo define normal values for synovial thickness in the healthy pediatric knee and wrist on MRI after intravenous gadolinium contrast administration. Secondary ObjectiveTo evaluate possible age-dependent variations in normal values…
The study aims to limit the use of anthracyclines and to reduce the dose of ATRA. Another aim is to stratify treatment by risk group: standard risk - WBC <10 x 109/l : high risk - WBC >=10 x 109/l. Furthermore this study aims to…
Primary objective:To determine sAF levels in children and young adults with T1DM and in children with obesity with or without T2DM and determine the correlation between sAF levels and HbA1c in children and young adults with T1DM and in children with…
Primary objective is to assess the reliability and assess the reliability and construct validity of the Repetitive Movement Test (RMT) as a measure of spasticity in children with CP scheduled for ITB treatment, between 6-18 year.
Using a variety of methods, we try to determine the dynamics of the chewing movements in typically developing children and children with CP. The methods are, in some degree, complementary to each other. Given the limitations of the methods we need…
The primary study objectives are as follows:-To evaluate the pharmacokinetics (PK) of golimumab in pediatric subjects aged 2 through 17 years with moderately to severely active UC.-To evaluate the safety of golimumab in pediatric subjects aged 2…
To determine the appropriateness of scale content of the preliminary CLEFT-Q scales by age and culture and to identify unclear or ambiguous items, instructions and response options
The primary objective of this study is to assess the potential clinical efficacy of HGT-1410administered via a surgically implanted IDDD in patients with MPS IIIA. Efficacy will bemeasured as a meaningful amelioration in the progression of cognitive…
Objective: Development of an instrument to objectively assess arm-hand skilled performance in daily life in typically developing children, children with CP and adults who suffered a stroke.
Our goal is to develop a standardized and validated Early Language Screening instrument (ELS-NL) for speech and language delays in children from 1 to 6 years of age living in the Netherlands.
To externally validate the accuracy of a host-response based diagnostics for differentiating between bacterial and viral etiology in pediatric patients aged 2 to 60 months with LRTI or FWS.
To determine the differences in brain activation during (un)healthy food choice between normal weight and overweight groups of children (10-13 y) and their parents and relate those to subject characteristics.