To determine the differences in brain activation during (un)healthy food choice between normal weight and overweight groups of children (10-13 y) and their parents and relate those to subject characteristics.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
overgewicht en obesitas
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
BOLD signal change during food choice and food viewing task.
Secondary outcome
Relation of BOLD signal change to subject characteristics.
Scores on of the liking of the food and the perceived healthiness.
Scores on the neuropsychological measures.
Background summary
The I.Family project is an EU funded FP7 project with the aimed at of
investigating the determinants of food choice, lifestyle and health in European
children, adolescents and their parents. Obesity is one of the main
determinants of avoidable ill health. In Europe, significant portions of the
population are overweight or obese. The lack of long-term effective treatment
puts the focus on prevention, which will have to start early in life since by
adolescence, since young people who are overweight are at high risk to become
overweight or obese adults. The question is what causes some children to become
overweight while their peers maintain a healthy weight? Diet, i.e., the daily
choice of foods, is thought to play a large role in these individual
differences, in interaction with genetics and environment. A better
understanding of tThe neural correlates of (un)healthy food choice in children
and their parents will give us more insight into the determinants of healthy
eating behavior in general and that in children in particular. By comparing
children*s responses to those of their parents the unique effects of age can be
assessed in isolation.
Study objective
To determine the differences in brain activation during (un)healthy food choice
between normal weight and overweight groups of children (10-13 y) and their
parents and relate those to subject characteristics.
Study design
Observational study.
Study burden and risks
This type of paradigm poses no risk. Participants will have a 40 minute MRI
session during which they will perform a 20 minute food choice task and a 8
minute food viewing task. Functional MRI is a commonly used technique which is
considered to be safe. Additionally, measurements will be done to assess
relevant subject characteristics. In summary, the risk associated with
participation is assessed as low and the burden as minimal.
Heidelberglaan 100
Utrecht 3584CX
NL
Heidelberglaan 100
Utrecht 3584CX
NL
Listed location countries
Age
Inclusion criteria
Healthy
Children: age 10-13 y
Children: age-corrected BMI between 20 and 25 kg/m2 or 25-35 kg/m2
Parents: age 28-48 y
Parents: BMI between 20 and 35 kg/m2
Exclusion criteria
Left handed
Presence of metal in the body incompatible with MRI scanning
Having a special diet (e.g. to lose weight, medically prescribed diet in the past 6
months, no meat etc.)
Highly restrained eating.
Having a food allergy
Alcoholconsumption > 28 units/week
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL43992.041.13 |