227 results
To evaluate the validity of grip work and self-perceived fatigue measured with the eforto® system for monitoring hip fracture recovery and insight in resilience.
The primary objective of this study is to determine brain activation in response to olfactory (orthonasal) exposure to different fat levels contained in a ecologically-relevant fat source.
The primary objective of this secondary prevention study is to evaluate the efficacy, safety, pharmacodynamics, and pharmacokinetics of gantenerumab, an anti-amyloid antibody, in amyloid-positive, cognitively unimpaired participants at risk for or…
To compare the post-prandial muscle protein synthetic response following ingestion of a whole-food meal (560kCal; 30g protein total) before and after a 8-week passive heat treatment intervention in healthy older men and women.
The primary objective is to investigate the effect of 6 weeks porcine protein supplementation versus an isocaloric carbohydrate (maltodextrin) on the composite endpoint of physical recovery.
We will investigate how safe the study device DV3395-C1 is when it is taken in by healthy participants. We will also look at the passage (i.e., gastrointestinal transit time) and activation of the study device. For this, we will see if the device…
Although the optimum length of alcohol avoidance training has been studied, little is known about the impact of the distribution of these sessions over time. As a result no guidelines or recommendations exist on whether AAT sessions should be spaced…
The aim of this study is to determine NET availability in patients with neurodegenerative diseases to characterize NA system degeneration in people with Alzheimer's disease, Parkinson's disease (with and without dementia) and with…
Primary Objective: To test whether the Feeling Safe-NL programme is more effective in improving wellbeing over time than CBTp (from baseline to 18-month follow-up).Secondary objectives: To test whether the Feeling Safe-NL programme is more effective…
The following questions will be addressed in the PARASOL study• Is the proposed study design feasible?,We will set up the study as a randomized pilot study to evaluate if patients are willing and able to participate in a randomized trial, i.e. are…
To develop an innovative magnetic resonance imaging (MRI) protocol(M-ILD) for accurate phenotyping and sensitive monitoring of therapy in ILD patients.
To our best knowledge, there are no studies on the preference of OSA patients for one or another MAD type based on its design characteristics. Therefore, the main objective of the study is to compare these MADs on the aspect of preference of…
The primary aim is to investigate if the weightbearing line alignment using a full-leg radiographic image results in more symmetrical frontal plane hip- and knee moments during gait. As a secondary aim, we will evaluate a) the relationship between…
The primary objective is to investigate if the stress-induced dynamics across stress systems are impaired in patients with CT-related depression compared to non-CT-related depression and healthy controls. The secondary objective is to examine how…
Primary objective: Explore, quantify and interpret the effect of 4-week intervention with 2 x 109 spores of BSCU1 on fecal sIgA, in healthy adults, elderly and 3-6 year old children.Secondary objectives:Explore, quantify and interpret the effect of…
The primary objective of this study is to evaluate the effect of single daily SC administration of elamipretide for 48 weeks on the distance walked (in meters) on the 6-minute walk test.The secondary objectives of this study are:- To evaluate the…
The main objective of the current project is to assess postprandial metabolic responses when graded amounts of whole-food dairy products are incorporated in a breakfast . Furthermore, we aim to explore the potential of jumping exercise to enhance…
In this study, we will investigate how quickly and to what extent etrumadenant is absorbed, transported, and eliminated from the body. For this study, etrumadenant is radioactively labelled with carbon 14 (14C). In this way, etrumadenant can be…
To investigate the effect of adding PIFM strengthening exercises to a functional exercise program compared to a functional exercise program alone on maximum gait speed in mobile older adults. The secondary objective is to also investigate the effect…
To confirm our previous findings that both TUS and auditory cuing decreases MEP amplitude in an independent sample using a more efficient design. Reducing the number of principal conditions will benefit data quality and allow for better estimation…