5311 results
To fully characterize skeletal muscle strength and endurance, phenotype and muscle fiber type-specific satellite cell content in frail elderly as compared to those elderly that do not classify as frail according to clinical criteria.
To investigate the effect of AMG 785 compared to placebo on functionalhealing as measured by the timed-up-and-go test (TUG) over Weeks 6 through 20 in subjectswith fresh unilateral low energetic hip (intertrochanteric or femoral neck) fracture
Is it possible to reconstruct intraoperative left ventricular end-systolic pressure-volume relations from a combination of non-invasive finger arterial blood pressure measurements and transoesophageal echocardiography in patients undergoing surgery?
The aim of this study is to evaluate an intervention program consisting of group motivational interviewing (GMI), supported by a social media platform, and/or environmental modifications, to decrease the need for recovery in office employees by…
Primary objectiveThe primary objective is to evaluate the effectiveness, safety, and tolerability of increasing doses of tapentadol PR (300 mg per day after run in, up titration to 500 mg per day) versus a combination of tapentadol PR (300 mg per…
The primary objective of the PROTI study is to establish whether patients can correctly determine which treatment assignment they received during the randomised phase of the trial.The key secondary objective is to compare the rate of withdrawal from…
Primary Objective: The primary goal of this research project is to evaluate the effect of a rockered shoe on walking and running biomechanics in healthy athletes and athletes with Achilles tendinopathy. The reason for using a patient group is that…
Determine whether feedback by means of motivational gaming can (partially) restore cognition-related deviations in motor performance as seen in back challenging conditions in CLBP patients.
This study aims to determine to which degree the offered help - according to our treatment program - for familymembers and partners of murdered persons helps to treat complicated grief and PTSD (Murphy, 2006, Shear et al 2006) and to gain insight…
Objective: The main objective is to test the preference for sweet and saltwater solutions in infants that started weaning exclusively with fruit or with vegetables. Acceptance of sweet and salt intensity is compared between the fruit and vegetable…
The primary objective of this study is to assess the efficacy of Ecopipam to reduce self-injurious behaviors (SIB) in adults and children with Lesch-Nyhan Disease (LND) in an outpatient setting. The secondary objectives of this study are to assess…
The evaluation of the safety and feasibilty of the Photopill capsule treatment in healthy volunteers, a phase 1 trial
The primary objective is to establish whether prefrontal compensatory mechanisms during working-memory performance may be enhanced by working-memory training, both in healthy older adults and MCI patients. The secondary objective is to establish age…
The primary objective of this study is to investigate the effect of - short vs. long - oro-sensory exposure combined with a gastric load - low vs. high in energy -, on gastric emptying rate. As secondary outcome we want to investigate the effect of…
In this phase II study, the toxicity and treatment effects of early donor derived CD4+ lymphocyte infusion, three months after allo-SCT, will be evaluated
The aim of the study is to test the hypothesis that susceptibility to and severity of certain infectious and inflammatory diseases can be explained by the interaction between the genome, microbiome and immunological responses: i.e. presence of…
Primary Objective: Our primary objective is to determine if it is acceptable to patients in the trauma clinic for orthopaedic/trauma surgeons, orthopaedic/trauma nurses, and/or social workers in the trauma clinic to screen for IPV.Secondary…
Primary objective: prospective evaluation of the relationship between lean body weight and anti-Xa activity of 5700 IU nadroparin 4 hours after subcutaneous administration in morbidly obese patients.Secundary objectives: - Correlation between other…
In the present study the prevalence of and risk factors for vitamin D deficiency will be determined in a patient population with a fracture in the upper or lower extremity.
This study primarily aims to explore changes in physical activity pattern and energy expenditure in head and neck cancer patients, during and after treatment with surgery with or without (chemo)radiation. The secondary aim of this study is to gain…