130 results
The purposes of this long-term mutli-center study are: - To compare the long-term (10-year) radiographic and clinical outcomes of new E-Poly* liner in primary total hip arthroplasty with the conventional ArcomXL® polyethylene liner.- To compare the…
BoneMaster ITo perform a comparative assessment between the clinical, bone remodelling, and radiographic outcomes (as measured with RSA) of the conventional Hydroxyl-Apetite (HA) Taperloc stem compared with Taperloc stem with additional BoneMaster®…
The purpose of this study is to show no difference in the outcome with abduction treatment versus no treatment in stable hip dysplasia between the age of 3 and 6 months.
The aim of this study is to develop an immortalised B-cell line derived from MG patients. This antibody producing cell line will be used for different applications:- The establishment of new passive transfer disease models for MG- The identification…
Within WP6 of a EU Seventh Framework project, we will investigate associations between purinergic receptor SNPs and osteoporosis risk in humans. Genetic data from a fracture cohort in The Netherlands with high prevalence of osteoporosis will be…
The research question of the main study is: What are the short- and long-term effects and costs of helmet treatmentcompared to a wait-and-see regimen for a period of 6 months on skull asymmetry in children withmoderate to severe DP.The objective of…
The primary objective is to determine if intra-articular etanercept therapy reduces the clinical signs and symptoms of inflammatory arthritis and improve outcome (beneficial effect). The secondary objective is to study safety and to analyse…
To compare two revalidation protocols with reference to the ACL reconstruction
The objective of this study is to demonstrate superior efficacy and evaluate the safety of MACI Implant compared with arthroscopic microfracture in the treatment of patients (aged 18 to 55 years old) with symptomatic articular cartilage defects of…
What is the most adequate treatment for people with partial meniscectomy?
To show whether Active C disc prosthesis is more effective than anterior discectomy with or without interbody fusion 1 year after surgery. Moreover, the incidence of adjacent disc degeneration will be evaluated 5 years after surgery.
The objective of the study is to determine the validity of MRI imaging to quantify changes in the CMC 1 joint in patients with osteoarthritis and how do these changes relate to functional status. The validity will be determined by comparison with…
The aims of this research proposal are to detect; 1) which early (degenerative) changes occur in bone, cartilage and menisci in patients with an acute complete ACL rupture, 2) at what point of time after the initial injury do these early changes…
The purpose of the study is to compare the functional result of CFP stem THA with conventional uncemented straight stem THA
Because the increasing fall problem, mainly due to an impaired gait and balance ability, this study will investigate fall risk by detecting fall related movement characteristics. Based on the promising results using accelerometry for accurate and…
The aim of this study is to identify direct markers of muscle and adipose tissue hypoxia in COPD and CHF patients in relation to the altered muscle oxidative phenotype and the putative mediators HIF-1α and PPARs/PGC-1. Insight in the underlying…
This study will investigate the relationship between autonomic nervous system function and pain in fibromyalgia, with a specific emphasis on awareness of bodily sensations, also refered to as interoceptive awareness, as a potential modulator of pain…
This project focuses on injury prevention-related cost-effectiveness of the "F-MARC Bricks".We hypothesize that the exercises of the *F-MARC Bricks*, integrated in the warm up, reduce injury incidence and/or injury severity and…
The aim is to gain basic dynamic information for an upcoming accuracy studies whereby the diagnostic value of one of the both will be determined. understanding motion patterns will enable us to set up new definitions for diagnosing ligamentous wrist…
The primary objective of this project is to contribute to the knowledge of the optimal medical care of DMD patients with regard to the optimal level of physical activity by examining the effects of training primarily upon muscle endurance and/or the…