480 results
The primary objective of this study is to further evaluate the safety and tolerability of pegaptanib sodium in subjects with DME.
To determine the beneficial effect of a single dose of 150 µg clonidine as an adjuvant to chirocaine in retrobulbar block.
The primary objective of this study is to assess the safety and efficacy of voclosporin as therapy in subjects with active noninfectious uveitis involving the intermediate and/or posterior segments of the eye (i.e., anterior + intermediate-,…
The primary statistical objective of this study is to describe mean differences in corneal staining (type and area), for OPTI-FREE EverMoist Multi-Purpose Disinfecting Solution compared to baseline.
In this study, we will systematically investigate the influence of distractors on target processing in patients with Duane Syndrome. These patients are impaired in executing eye movements in horizontal directions. It will be investigated whether a…
Primary: To assess the effects of PRM-151 compared to placebo on the success of trabeculectomy by reducing post-surgical scarring in glaucoma patients who have undergone primary trabeculectomy, evaluated at day 120.Secondary: To assess the safety…
The objectives of this study are to assess and compare bilateral uncorrected distance visual acuity and distance spectacle independence post bilateral implantation of AcrySof Toric IOLs and monofocal IOLs.
The purpose of this pilot study is to compare the perception of straylight in patients with CE marked multifocal intraocular lenses, measured with 4 different straylight measuring devices..
1. To determine if zinc supplementation in AMD patients has a direct measurable effect on the complement system explaining the mechanism through which this substance exerts its influence on AMD progression.2. To determine whether this proposed…
This study has two major goals. The first goal of this study is to evaluate whether the disabilitating effects of crowding can be reduced by the use of a magnifier early in life. The second goal is to investigate motor and visual development of…
To investigate inter-examiner variability of the alternate prism and cover test (APCT) measurements of ocular deviation at near and distance fixation, and to compare variability between adults/teenagers and children.
Development, optimization and implementation of retro-orbital fibroblast cultures in our laboratory.
To compare the effect on the corneal endothelium of ICSAC during vitrectomy.
The study objectives are:- to characterize the biotransformation pathways, the routes and rates of excretion, and total recovery of the 14C-labeled research medication and its radiolabeled metabolites- to characterize the pharmacokinetics (PK) of…
The primary objective of this study is to investigate whether consumption of a dried lutein-enriched egg-yolk containing beverage significantly increases serum lutein concentration in healthy volunteers.A secondary objective is to investigate…
To investigate the extent to which performance measurements in a driving simulator discriminate between glaucoma patients and a control group.
- Analyse the effect of the toric T2 intraocular lens on quality of vision, compared to a standard monofocal intraocular lens. - Analyse the satisfaction of patients with their visual acuity with the toric T2 intraocular lens, compared to a standard…
Main objectives: 1. to investigate the prevalence of vision abnormalities in 9- and 10 year old children; 2. to investigate the percentage of these vision abnormalities that were detected the VOV screening programme;3. to investigate whether these…
Primary: efficacy, assessed by best-corrected visual acuity and SD-OCT of 1 eye (*study eye*). Secondary: retina anatomy of the study eye, safety and tolerability, PK, PD.Exploratory: Best-corrected visual acuity, SD-OCT and retina anatomy of the…
The purpose of this study is to investigate the genotype of a large group of CSNB patients for which the phenotype is already known. We hope to increase our understanding of CSNB in order to improve diagnosis, to offer more realistic prognoses and…