92 results
PROUD is a multicentre prospective study, using clinical factors in combination with additional tests with the aim to clarify more about the aetiology and pathogenesis of MS.
The primary objective is to study glaucomatous structural brain changes in a longitudinal manner, and how it relates to visual functional loss and glaucomatous retinal changes over time.
Dissection of etiology of myopia- identification of genetic risk factors- identification of environmental risk factors- evaluation of the long term safety of Artisan phakic intraocular lenses for the correction of high degree myopia
1. To determine if zinc supplementation in AMD patients has a direct measurable effect on the complement system explaining the mechanism through which this substance exerts its influence on AMD progression.2. To determine whether this proposed…
Development, optimization and implementation of retro-orbital fibroblast cultures in our laboratory.
In the present study, we will investigate if a monocular visual field defect - due to primary open angle glaucoma - influences the anatomical integrity of the visual pathways.
This study has the following goals: 1. Generation of normative values for full-field ERGs within single recording sessions according to ISCEV standard.2. To compare function (results of full-field ERG) with anatomy (retinal thickness on OCT) in…
To investigate if a vitamin B12 deficiency has a higher prevalence in LHON patients, during the acute phase of visual loss, then in a normal population.
To determine the effect of tube position in the anterior chamber on the corneal endothelium.
The major goal of this study is to develop a systematic and stepwise approach for dry eyes. First, it will be evaluated whether Tes glasses are a diagnostic tool for dry eye diseases. Second, it will be evaluated or it can make a distinction between…
The objective of this study is to investigate the use of retinal oximetry in children, between five and seventeen years of age, with (vitreo-) retinopathies and oxygen-related diseases of the retina by means of an Oxymap T1 fundus camera.
To detect ophthalmic differences between patients and controles. To detect (early) changes in the retina in (pre)symptomatic RVCL disease carriers, in order to find a *biomarker* for disease stage and progression.
To measure the quality of peripheral visual field in healthy volunteers and the effect of different corrective lenses on the peripheral visual field.
The primary objective of this study is:- To determine the potential difference in MT and RNFLT between treated and untreated patients with anisometropic or strabismic amblyopia. Secondary objectives are:- To determine the potential differences in MT…
To study the efficiency of visual information processing in patients with retinal disorders.
The objective of the study is to map in a standardized way the phenotype of carriers with known LHON mutations. We want to study the natural course of persons with LHON mutations by examining patients several times. Further, we want to study a…
We aim to investigate whether a relation between intestinal microbiota composition, mucosal integrity and translocation of bacteria into adipose tissue of the affected eye is related to the severity of Graves orbitopathy.
To study neuronal and ophthalmological characteristics of a newly detected clinical entity called slow vision which hampers visual perception and attention of the affected patients.
The objective of this study is to analyse the retinal oxygenation in adults with the Oxymap T1 in patients with amblyopia and untreated or treated (vitreo-) retinopathies and compare them to a reference group of healthy eyes of amblyopic and Coats…
The key objectives of this study are to identify both the genetic background and pathophysiological mechanisms that underlie CSC. To achieve this we will: 1) Perform genetic analysis and ophthalmological examination in a cohort of sporadic CSC…