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Development and Validation of novel methods for Quantitative Magnetic Resonance Imaging of Tissue Properties

To develop and test new MRI sequences that enable new imaging contrasts and enable depiction of tissue properties that can not be depicted with current techniques.

Comparison of different transfusion strategies for red blood cell transfusion dependent MDS and MPN patients - a cross-over study with remote patient monitoring

Compare the effect of three different RBC transfusion strategies* (Standard of care (SoC), SoC+1 and SoC+2**) on heart rate in a population of chronically transfused patients (with on average at least 1 RBC transfusion each 8 weeks as personal…

A 24-week with possible extension, prospective, multicenter, randomized, double blind, placebo-controlled, 2-parallel group with a randomization 1:1, phase III study to compare efficacy and safety of oral masitinib to placebo in treatment of patients with Smouldering or Indolent Severe Systemic mastocytosis with handicap, unresponsive to optimal symptomatic treatment

To evaluate the efficacy and safety of oral masitinib versus placebo in the treatment of patients suffering from Smouldering or Indolent SevereSystemic mastocytosis with handicap unresponsive to optimal symptomatic treatment.

Glymphatic dysfunction in cognitive impairment: a memory clinic study

The current study aims to obtain a better understanding of glymphatic dysfunction in dementia of the Alzheimer*s type and its preclinical stages.The main objective of this study is to improve our understanding of the potential link between…