To develop and test new MRI sequences that enable new imaging contrasts and enable depiction of tissue properties that can not be depicted with current techniques.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Healthy human body: primarily heart, esophagus and brain
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Parameters of image quality and endogenous contrast sensitivity: artifacts,
signal to noise, contrast to noise, reproducibility, accuracy; Reference range
in healthy subjects for novel quantitative imaging biomarkers.
Secondary outcome
N/A
Background summary
Novel MRI sequences have to be evaluated in healthy volunteers in order to
identify areas of improvement for the development and to assess the additional
value of these sequences in the visualization and quantitative assessment of
tissues and organs.
Study objective
To develop and test new MRI sequences that enable new imaging contrasts and
enable depiction of tissue properties that can not be depicted with current
techniques.
Study design
Observational Diagnostic Study
Study burden and risks
Burden: MRI examination for a maximum of 120 minutes; Exposure to acoustic
noise. No pharmacological or other invasive interventions will be performed.
Risks: The risk of participation is negligible.
Lorentzweg 1
Delft 2628CJ
NL
Lorentzweg 1
Delft 2628CJ
NL
Listed location countries
Age
Inclusion criteria
Healthy subject (defined as a volunteer free of any signs and symptoms of
disease or disorders that could influence the MRI scan)
At least 18 years old and not older than 60 years old
Proficiency in Dutch or English (all relevant information is only available in
these two languages)
Signed informed consent
Exclusion criteria
Subjects with contra-indication to a MRI exam.
Subjects with metal implants.
Woman who are pregnant or lactating
Subjects who are claustrophobic
Subject having any physical or mental status that interferes with the informed
consent
Subjects who use medication that could interfere with the protocol
Subjects who do not want to be informed in case of incidental finding
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL73381.078.20 |