236 results
A post marketing surveillance study to assess safety, clinical performance and survival of the uncemented Glenoid Affinis vitamys Uncemented Glenoid Affinis Vitamys total prosthetic shoulder replacement. All implants already bear the CE-marking.
Primary Objective: To study the effect of different treatment approaches - existing of conservative management, pharmacological treatment and surgical treatment - on sexual function in patients diagnosed with endometriosis. Secondary Objective(s):…
Primary Objective:The study aims to assess freedom from AF ten years after the procedure without the use of antiarrhythmic drugs in patients who underwent thoracoscopic ablation in advanced AF with or without GP ablation. Secondary Objectives:1. To…
To determine the real world response to standard of care CAR T-cell therapy, in order to better understand the intrinsic and extrinsic factors related to treatment success or failure.
The primary objective is to assess if consuming a slush puppy combined with glycerol at 0°C can reduce the thermal strain during a three hour march in physically active men compared to an isotonic sports drink at 33°C and a slush drink at 0°C. The…
To evaluate the feasibility, safety and potential efficacy of acupuncture in children with FC. The results of this study will be used to design a future randomized controlled trial (RCT).
The objective of this study is to demonstrate the clinical performance of VENTANA PD-L1 (SP263) CDx Assay in terms of its ability to identify patients with metastatic NSCLC who may benefit from treatment with acasunlimab (GEN1046) in combination…
Current laboratory tests for hypersensitivity are not sensitive of do not exist for certain allergens omong which medical drugs. To objective is therefore to optimize existing in vitro tests (lymphocyte activation and proliferation test, cytokine…
To investigate oxidative stress levels in the plasma and urine of late preterm and term newborns treated for PPHN in the NICU.
The primary objective of this study is to evaluate the clinical performance of the [REDACTED] PD-L1 [REDACTED] CDx Assay in terms of its ability to identify patients with squamous metastatic NSCLC (mNSCLC) who may benefit from treatment with […
The primary objective of this feasibility study is to provide an initial assessment of OA/US imaging to distinguish between benign and malignant thyroid nodules using HbO2 and HbR as the primary biomarkers.The secondary objectives are:- To…
The objective of this clinical trial is to demonstrate that ablation with the TactiFlex* SE Ablation Catheter, Sensor Enabled* (TactiFlex PFA), in conjunction with a compatible PFA and/or RF generator, is safe and effective for the treatment of…
The primary objective is to improve the accuracy to predict glioma genotype of our previously developed algorithm *PrognosAIs* by adding advanced MRI acquired before surgery. The secondary objective is to learn the relationship between MRI signal…
The primary objective of the VRAPT Arousal Pilot Study is to explore the feasibility, appropriateness and acceptability of the developed VRAPT Arousal intervention among forensic psychiatric inpatients and forensic healthcare practitioners working…
The purpose of this observational pilot study is to evaluate the extent to which the combined glucose, heart rate, blood pressure, and other outcome patterns, collected from wearables, are associated with the severity of micro- and macrovascular…
The primary objective is to evaluate the supporting mechanism of the pelvic floor for a Gellhorn pessary in patients with pelvic organ prolapse immediately after insertion and one week after insertion of the Gellhorn pessary.Secondary Objectives: •…
Objective: What pre and postoperative factors are associated with limb salvage in patients undergoing superficial venous arterialization (SVA)?Secondary objectives: • What is the vascular anatomy and blood flow in the associated veins in patients…
The primary objective of this study is to evaluate the clinical performance of the [Redacted] PD-L1 [Redacted] CDx Assay in terms of its ability to identify patients with non-squamous metastatic NSCLC (mNSCLC) who may benefit from treatment with […
In this proposal, we will collect samples from both US and international corneal ulcers, identify etiology, AMR, and local host immune response, and correlate with presentation and outcome.Specific Aim 1. Worldwide surveillance of organisms…
Measurement of intestinal oxidation-reduction potential using a smart sensing ingestible and its relation to active UC and CRC.