612 results
1) To investigate the effect of atomoxetine on resting-state fMRI measures of network functional connectivity.2) To assess the effect of atomoxetine on several task performance variables, that are hypothesized to reflect tonic LC-NE activity.3) To…
To assess the effect of short term starvation and short term high fat diet on orally administered acetaminophen metabolism in healthy subjects.
The primary objective of this study is to assess if cannabinoids modulate sweet taste intensity and liking.
The aim of the study is to investigate the effects on time trial / cycle test performance after ingestion of Snelle Jelle 'kruidkoek' and water, banana and water, or only water.
The main objective of our study is to explore whether LTH and FMD are correlated. Main secondary objectives are to investigate whether the LTH response is largely NO-mediated and whether drinking beetroot juice acutely improves both FMD and LTH.
To this end, two study protocols have been developed, one concerning the *target group* of overweight children (aged 12-16), only including non-invasive measurements, and one targeting adult overweight participants (aged 18-45), allowing for…
- To investigate the biochemical response of ITF2984, defined as a reduction in (random) GH < 1.0 mcg/l and/or normalization of IGF-1.- To investigate the biochemical response of ITF2984, defined as a reduction of GH to no more than 2.5 mcg/l…
The main objective of this study is to investigate the effect of a single tDCS session in children with mild CP on different motor tasks. The second objective is to identify the optimal site of stimulation. In tDCS research the electrodes can be…
Determining the effect of short term ProManna intake on physiological parameters, notably biomarkers of oxidative stress. This pilot study serves to investigate whether ProManna intake leads to any changes in baseline levels for oxidative stress…
Study I: To assess the bioavailability of Zinc from full cream UHT milk, fortified full cream UHT milk, a supplement, and raw milk.Study II: To assess the potential enhancing effect of milk on Zn absorption from intrinsically labelled rice (as a…
In the current study we will measure ventilatory response, as assessed by ventilatory carbon dioxide responses to the administration of oxycodone during three conditions: a *low alcohol condition*, a *high alcohol condition* and a *no alcohol…
Here we will perform a proof of concept study on the ability of the antidepressant tianeptine to prevent respiratory depression from the opioid alfentanil in humans.
To gain insight in the neurobiological mechanisms behind oxytocin effects on human social-emotional behaviour.
The primary objective of this study is to determine the antialbuminuric response of vitamin D analogue in addition to ACE-inhibitor and low-sodium diet, in renal patients.
The present study aims to determine the bioavailability of hesperidin when micronized and non-micronized, when S-enantiomeric enriched and racemic, and when incorporated in a lozenge compared to a capsule, such that the appropriate dosage form can…
Primary Objective(s):1. To determine whether aging associated cognitive impairment can be attenuated by roflumilast administration as assessed by cognitive battery tests.Secondary Objective(s):1. To determine whether brain electrical activity (ie,…
The main objective is to gain insight into the temporal differences between the perceived sweetness and irritation of carbonated beverages with sucrose and/or Stevia. More specifically, objectives of part 1 of the study are:- To assess the overall…
Our primary aims are 1) to test with observational and electrophysiological techniques whether intranasal oxytocin administration to mothers of young infants increases their defensive reactivity and protective approach responses in mildly…
To investigate responses of the autonomic nervous system (ANS) and facial expressions to sensory-specific satiety.
The objective of this study is to validate MRI as a functional measuring device for directly monitoring gastric emptying in vivo, while creating an overview of the influence of viscosity and nutrient density on gastric emptying times.