68 results
To assess the post-operative quality of recovery after robot-assisted as compared to open extended lateral pancreaticojejunostomy.
The primary objective is to assess if consuming a slush puppy combined with glycerol at 0°C can reduce the thermal strain during a three hour march in physically active men compared to an isotonic sports drink at 33°C and a slush drink at 0°C. The…
The primary objective is to perform a clinical validation of the analytical method for dried blood spot microsampling of cabozantinib, pazopanib, sunitinib, Lenvatinib, nivolumab, ipilimumab, pembrolizumab, atezolizumab or bevacizumab. The secondary…
The aim of this project is to unravel whether BPD after the neonatal period is a chronic inflammatory disease, and if markers of inflammation and/or oxidative stress are related to pulmonary morbidity in patients with BPD. Based on these findings,…
Primary Objective: Compare visual acuity between adults born prematurely and adults of general population born at full term.Secondary Objective(s): o Compare other anatomical and functional ocular outcomes (retina, macula thickness, refraction,…
The primary objective of this pilot study is therefore to investigate the effects of TENS on brain activity in pwMS measured with fMRI.
The aim of this study is both a feasibility study to gain a comprehensive understanding of the feasibility, satisfaction and impact, and trends of the effects of a physical exercise and nutritional intervention in patients who will be treated by a…
Primary Objective: To investigate the agreement between cuffless blood pressure monitoring values and ABPM values in patients treated for hypertension.- Expressed as a mean difference between cuffless BP monitoring values and ABPM values- The…
To assess the feasibility of using the developed medication management centre to empower polypharmacy patients, thereby improving drug safety. Secondary objectives are to explore if the tool is able to identify patients at risk for a drug-drug-gene…
The primary objective of phase 1 is to validate a new ELISA measurement that can determine hIAPP oligomers reliably in plasma, and of phase 2 is to correlate pathogenic oligomer hIAPP (in plasma and skin) with pain and sensory disturbances in CIAP…
Patients with ABI follow a multidisciplinary rehabilitation program. This program is very intensive and also requires a lot from loved ones. The burden can be reduced by partly delivering the program from home.The aim of this project is to implement…
Primary Objective: to assess brain kinetics of glutamate, GABA and dopamine and the associated functional connectivity of the mesocorticolimbic circuit during the absorption and elimination phase of JWH-018, as compared to the control condition.…
The primary aim of this study is to determine the causal relationship between the accumulation and inflammation of perivascular adipose tissue (PVAT) and insulin-stimulated glucose uptake in skeletal muscle, measured using dynamic PET-CTA, in…
We aim to collect blood cells from 40 patients with monogenic epilepsy, with a preference for patients with a pathogenic variant in SCN1A, reprogram these cells into iPSCs and use these iPSCs for differentiation into neurons and neuronal organoids…
Primary Objective: To assess the acute subjective drug effects (good/bad drug effect, drug liking/wanting, anxiety), cognition (attention, working memory, information processing speed, verbal memory, verbal fluency, motor inhibition), and…
The aim of this study is to investigate whether the transfer of antibodies from mother to infant is less effective in infants with intrauterine growth restriction (FGR) compared to term-born infants without intrauterine growth restriction or who are…
The primary objective of this explorative study is to investigate the effect of 3-month preparation period of regular walking exercise prior to the Nijmegen 4-Day marches on objectively measured AF burden (primary parameter), self-reported AF burden…
To evaluate the acceptability and effectiveness of a deepfake victim-perpetrator confrontation in young adults with sexual violence-related PTSD.
The primary objective is to identify clinical and biological measures that discriminate paediatric ME/CFS and post-COVID patients from healthy controls based on either clinical (based on physiological tests and questionnaires) and biological (based…
To establish whether the decrease in pulmonary function as a result of wearing a neoprene suit is caused by restriction or obstruction, and which effect is has on pulmonary volumes.