229 results
Considering the paucity and the variability of data regarding the clinical control of infection in patients presenting a prosthesis Joint Infection (PJI) later than 1 month after the arthroplasty and treated with DAIR + suppressive antibiotics…
This study has been transitioned to CTIS with ID 2024-513483-26-00 check the CTIS register for the current data. To assesses the efficacy of Tinlarebant in slowing the rate of growth of atrophic lesion(s) in adolescent subjects with STGD1.
To determine the effects of the PCP+SM compared with usual care on BP control in adults with hypertension. To determine the effects of the PCP+SM compared with usual care on antihypertensive medication use in adults with hypertension. To determine…
This study has been transitioned to CTIS with ID 2023-504999-25-00 check the CTIS register for the current data. To investigate wether the treatment of children and adolescents with AML can be improvedby means of:1) improved risk-group adapted…
To investigate if dried blood spot sampling of vancomycin and creatinine leads to less outpatient visits regarding vancomycin therapy compared to conventional sampling in OPAT service.
The primary objective is to compare a composite endpoint of major CV events and all-cause death between control and intervention group.Secondary objectives are the comparison of patient-centered outcomes between the two groups.
The aim of the study is to establish depression and suicide prevention reaching students who attend special education.The primary goal is to evaluate the effectiveness on depressive symptoms of a screening and prevention program for adolescents who…
Primary Objective:To investigate whether there is a difference in the number of participants that will reach optimal LT4 supplementation (i.e. stability of TSH levels and symptoms) in the breakfast group compared to the fasting group.Secondary…
To determine the effect of a 6-month eucaloric very-low-carbohydrate ketogenic diet on IGF-I levels in adult acromegaly patients.
To compare miLOOP assisted cataract surgery and conventional surgery with respect to the energy needed for phacoemulsification and loss of corneal endothelial cells.
To test whether valve surgery plus medical therapy is superior to medical therapy alone for treatment of endocarditis.
- Part I: determine the difference in microcirculatory perfusion between three different prime fluid strategies in patients undergoing elective cardiac surgery with cardiopulmonary bypass.- Part II: To determine the effect of limiting hemodilution…
The primary objectives of this investigation are to evaluate whether pre-acquired Amycard ECGI map-guided LV lead placement (I) improves CRT volumetric response compared to non-guided (empiric) LV lead placement, and (II) reduces the distance to LV…
To explore the safety, feasibility and net symptomatic effects of multiple intermittent hypoxia intervention sessions in individuals with PD. Secondary outcomes include exploring induction of relevant neuroprotective pathways as measured in serum.
Primary Objective: • To compare the efficacy of chemical ablation with phenol and RFA of the genicular nerves with conservative treatment in patients with chronic knee pain caused by OA, on the Oxford Knee Score (OKS) at six months follow…
This study has been transitioned to CTIS with ID 2023-508926-91-00 check the CTIS register for the current data. To determine non-inferiority of preoperative 6 weeks of VCE to VAD in the overall metastatic rapid response rate (MetRR) in newly…
This study has been transitioned to CTIS with ID 2024-510742-13-00 check the CTIS register for the current data. The primary objective is to compare the objective response rate (ORR) assessed per Response Assessment in Neuro Oncology for low-grade…
This study has been transitioned to CTIS with ID 2023-505512-37-00 check the CTIS register for the current data. The primary objective of the randomized part of the protocol is to investigate if a conditioning regimen containing one alkylator (Bu)…