229 results
To assess the efficacy of early mechanical left ventricular unloading and standard of care (inotropes/vasopressors) versus inotropes/vasopressors alone (standard-of-care) in patients with ADHF and signs of cardiogenic shock.
The main objective of the proposed study is to investigate the effect of ctVNS as a means to counteract the effects of SD on cognitive performance during and after SD. This will be tested using both well-controlled, established cognitive desktop…
To investigate the feasibility of increasing preoperative dietary fiber intake in CRC patients undergoing surgery via 1) personalized dietary advice (Vezel-UP tool), or 2) vegetable product containing natural fibers (WholeFiber) compared to 3)…
The main objective of the current study is to assess the impact of dietary collagen supplementation on human tendon protein synthesis.
Primary Objective: The performance in preventing intraoperative hypotension of a MAP treatment alarm of 72 mmHg compared to the performance of the HPI alarm. Secondary Objectives: - The correlation between the MAP signal and HPI signal - The…
The aim of the study is to investigate whether the use of telemetry monitoring leads to the promotion of early mobilization, by an improvement in mobilization and strength measurements, in rehabilitating ICU/MCU patients. Secondary goal is whether…
To assess whether the application of CARV for intra-medullary nailing of tibial shaft fractures results in a more accurate rotationalalignment of the tibia in comparison to conventional (e.g., eyeballing of the surgeon according to current practice…
This project aims to investigate peripheral and central neuroplasticity following an early (<13 weeks after injury) and intensive (8 weeks of 6 hours of additional therapy) upper extremity motor training program (EIUMT)…
Currently, available literature on costs and clinical effectiveness of MITLIF compared to OTLIF for patients with lumbar spondylolisthesis and degenerative foraminal stenosis is not sufficient. With a steep increase in the number of instrumented…
The current study aims to investigate two types of sleep interventions in night shift workers: a split sleep intervention strategy and a short sleep episode (powernap, max. 20 min) during a night shift. It will assess the effects of the two…
This is a feasibility designed to investigate the feasibility of collecting QoL information from patients via digital tools. By feasibility, we mean the assessment of the uptake of the tool, the compliance to schedule and the quality of the data…
The aim of the current study is to increase understanding of the effectiveness and efficiency of psychological treatment for patients with PTSD and to better personalize differential therapeutics.Key questions:1. Which generic predictors of…
The primary outcome of this study is the detection of clinical relevant adenomas (>= 5mm) in the ileal pouch.
Primary Objective: To evaluate the effect of kinesiotaping on number of patients with clinically meaningful pain reduction after 1 week in patients with acute traumatic injury in shoulder or chest wall, compared to sham tape and no tape (2…
To assess the feasibility of a larger study comparing HFNO with NIV as first line treatment in hypercapnic, acidotic AECOPD.
Primary Objective: The aim of this study is to research the effect of a computerized cognitive rehabilitation program (RehaCom) in post COVID-19 patients with cognitive complaints on their sustained and divided attention and their working memory.…
Primary Objectives:1. To evaluate target engagement attributable to G3P-01 use in volunteers with elevated galectin-3 (>= 16.0ng/mL)2. To evaluate tolerability of G3P-01Secondary Objectives:1. To provide samples for research and development…
The primary objective of this study is to test whether deepening post-treatment sleep each night of a 5-day treatment program for PTSD using EEG-guided acoustic stimulation, will result an augmented overall treatment effect. In addition, two…
Primary objective:• To evaluate the safety and tolerability profile of single intravenous doses of AST-004 given as a short loading intravenous infusion followed by a 6-hour continuous intravenous (IV) infusion in healthy adult subjects.Secondary…
This study has been transitioned to CTIS with ID 2024-516939-28-00 check the CTIS register for the current data. To compare progression free survival (PFS) between treatment with docetaxel or cabazitaxel and darolutamide versus treatment with…