The Objective of this study is to validate the new developed sensor fotoplethysmografie (MPA-16), that later can be used to better understand the local vasculature. And determining the feasibility / applicability of this test setup for patients.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
Verificatie op gezonde vrijwilligers
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main study parameter is the reliability and repeatability of the
measurement with the MPA-16.
Secondary outcome
-
Background summary
Photoplethysmography (PPG) is an optical technique for volumetric measuring of
an organ. PTT is determined as the time interval between the R-wave of the
electrocardiogram (ECG) to the foot of the photoplethysmogram. The PTT consists
of two components: the pre-ejection period (PEP), and the vascular transit time
(VTT). The VTT is the time for an arterial pressure wave to cover a predefined
distances. The VTT is known to be related to the local compliance of the
artery. Therefore the VTT can be used to assess the effect of diseases on the
peripheral vascular compliance and for example the vasomotor response. The new
developed sensor consists of a photodiode-array with 16 photodiodes with a
total distance of 12.5mm. The light source is a RED-led and an IR-led. Each of
the photodiode elements within the array measures a local PPG signal.
Study objective
The Objective of this study is to validate the new developed sensor
fotoplethysmografie (MPA-16), that later can be used to better understand the
local vasculature. And determining the feasibility / applicability of this test
setup for patients.
Study design
A observational, single center study conducted in the Erasmus Medical Center.
Study burden and risks
The measurents are without risk, they are all non-invasive.
Dr. Molewaterplein 50
3015GE
NL
Dr. Molewaterplein 50
3015GE
NL
Listed location countries
Age
Inclusion criteria
Healthy volunteers, aged 20-30 years old.
Exclusion criteria
o Cardiovascular diseases
o Peripheral vascular disease
o Diabetes
o Muscle or skeletal injuries in upper and lower limb
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL37054.078.11 |