The present study aims at comparing bedside JVP measurement using the so-called venous arch (veneuze boog) with modern echocardiography and NT-pro-BNP in patients referred for echocardiography with a suspicion of heart failure. The study also aims…
ID
Source
Brief title
Condition
- Heart failures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The primary outcome is the diagnostic performance of the index test (bedside
JVP measurement), compared with the two reference tests (echocardiography and
serum BNP concentration).
Secondary outcome
The secondary outcome is the feasibility of reliably measuring JVP at the
bedside. The subjective report of the residents concerning different aspects of
the quality of the measurement are used to establish this outcome.
Background summary
Incidence and prevalence of congestive heart failure are still increasing in
the aging population of the Western world as well as in Third world countries.
Diagnosing heart failure can be difficult. Nowadays, echocardiography and
circulating concentration of brain natriuretic peptide (NT-pro-BNP) are
considered gold standard in the diagnosis of heart failure. Bedside measurement
of the jugular venous pressure (JVP) is a simple methods of diagnosing heart
failure, but this measurement has been discredited in recent years. Reports in
the literature on the reliability of bedside JVP measurement vary considerably.
Bedside JVP measurement has never been compared to modern echocardiography and
simultaneous NT-pro-BNP measurement.
Study objective
The present study aims at comparing bedside JVP measurement using the so-called
venous arch (veneuze boog) with modern echocardiography and NT-pro-BNP in
patients referred for echocardiography with a suspicion of heart failure. The
study also aims at determining the feasibility of training residents in the
proper application of this method.
Study design
Consecutive patients referred to the echocardiography department of the OLVG
hospital with suspicion of heart failure (other clinical data such as *dyspnea*
and *edema* may fall into this category) are included in this single center,
prospective, double blinded trial. Just before or after the echocardiography,
the bedside JVP measurement is performed by residents in training (blinded for
the result of echocardiography). Blood is drawn for measurement of serum BNP
levels.
In this study design, the bedside measurement of the JVP using the venous arch
is regarded as the index test, as an easy tool to diagnose patients with heart
failure. The echocardiography as well as the serum BNP levels are regarded as
reference tests.
Study burden and risks
The patient will have to extend their stay at the echocardiography department
for ten minutes. There are no risks associated with JVP measurement and
venapuncture.
Postbus 95500
1090 HM Amsterdam
NL
Postbus 95500
1090 HM Amsterdam
NL
Listed location countries
Age
Inclusion criteria
Patients must be referred for echocardiography with a question of heart failure or clinical data that may fit into this suspicion. Patients must be 18 years or older and must be able to give informed consent.
Exclusion criteria
Acutely dyspnoic patients that cannot be properly investigated (for instance they cannot tolerate the supine position for a short period of time).
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL22721.100.09 |