Further investigate the energy cost for balance control in patients after stroke and to compare the energy costs of stroke patients and healthy controls during quiet standing with and without balance perturbations. The energy costs will be related…
ID
Source
Brief title
Condition
- Central nervous system vascular disorders
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Balance
*mean amplitude: the average COP distance to the origin of the mean-centered
posturogram
*sway path length: sum of the distances between consecutive points in the
conventional posturogram
*the 95% confidence circle area, which represents the area of the posturogram
with a circle that includes approximately 95% of the distances from the mean
COP (Prieto et al. 1996)
*normalized sway path length of the posturogram; measures the amount of
twisting and turning
*largest Lyapunov exponent; measure for local stability
*DFA (detrended fluctuation analysis); determines correlation in time
*sample entropy; measure for regularity
Energy:
*Oxygen consumption in milliliters/ minute/ kilogram
*Energy expenditure in Joules/ minute/ kilogram
Muscle activity:
*root mean square of the EMG data
Secondary outcome
*Berg Balance scale
*Medical status of the patient
Background summary
The energy cost during ADL tasks are higher for people with several disorders
of the human movement system and/ or the nervous system. A possible explanation
is an altered movement execution caused by the locomotive impairments, but it
is also possible that the increased energy demand is (partly) caused by an
increased energy cost for balance control. There is only limited data available
on the relation between balance control and energy cost in stroke patients. If
it is found that the energy cost for balance control is higher in stroke
patients, this information could be used to improve the rehabilitation program.
Study objective
Further investigate the energy cost for balance control in patients after
stroke and to compare the energy costs of stroke patients and healthy controls
during quiet standing with and without balance perturbations. The energy costs
will be related to different balance measures (COP-traject, Berg Balance Scale,
Electromyography (EMG)).
Study design
Balance and energy expenditure will be measured during five different
conditions while standing quiet on a force plate:
*Standing on firm surface
*Standing on firm surface while performing a dual task
*Standing on firm surface with eyes closed
*Standing on foam surface
*Standing with feet placed parallel against each other
Each condition lasts 2 minutes.
Furthermore, balance will be determined with the Berg Balance scale and energy
expenditure will be measured with a respiratory system. Muscle activity for
balance control (muscle activity of the Tibilialis anterior and Gastrocnemius
of the non-paretic leg (or dominant leg in healthy controls) will be measured
with EMG. Measurements will take place in Rehabilitation centre Heliomare.
Balance will be quantified with conventional and dynamical measures of the
COP-traject (obtained with a force plate).
These measures, the score on the BBS, the energy expenditure and the muscle
activity will be compared between groups and conditions. Furtermore, the
balance measures and the muscle activity will be correlated with the energy
expenditure.
Study burden and risks
The stroke patients are all able to stand for two minutes and therefore it is
expected that the risks of the measurements are minimal. During the
measurements at least one experimenter will be close to the subjects to
intervene if necessary. Furthermore, an aid will be placed in front of the
subjects, so that subjects can hold on to it when necessary.
van der Boechorststraat 9
1081 BT Amsterdam
Nederland
van der Boechorststraat 9
1081 BT Amsterdam
Nederland
Listed location countries
Age
Inclusion criteria
*Admitted to rehabilitation centre and diagnosed with stroke
*Able to stand without aids or assistance for at least 2 minutes
*Maximal score on Berg Balance scale of 45
Exclusion criteria
*Vestibular disease
*Cognitive and communicative disorders which could influence the protocol
*Medically unstable
*Use of medication that could interfere with balance control
*Non stroke related sensory or motor impairments that could interfere with balance control
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| CCMO | NL22526.029.08 |