The investigation of differences between morphine and piritramide concerning the incidence of postoperative nausea and vomiting and the time of onset of adequate analgesia.
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
pijn en misselijkheid
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
The incidence of nausea and vomiting
Secondary outcome
Time of onset of adequate analgesia.
Background summary
Postoperative nausea and vomiting occur frequently with the use of opioids. The
perception is that this complications occurs more frequently with morphine;
furthermore that the time of onset of analgesia takes longer with morphine
compared to piritramide, which was the opioid of choice in the past.
Study objective
The investigation of differences between morphine and piritramide concerning
the incidence of postoperative nausea and vomiting and the time of onset of
adequate analgesia.
Study design
double blind
Intervention
The intravenous injection of morphine of piritramide.
Study burden and risks
None
Postbus 4446
6401 CX Heerlen
NL
Postbus 4446
6401 CX Heerlen
NL
Listed location countries
Age
Inclusion criteria
Adult patients who undergo elective surgery under general anesthesia.
Exclusion criteria
The use of additional techniques of regional anesthesia.
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| EudraCT | EUCTR2007-000659-32-NL |
| CCMO | NL16524.096.07 |