The purpose of the proposed study is twofold. First, to test a process model of adaptation that distinguishes between the changes in life imposed by the illness (i.e., subjective cancer experience), the immediate (emotional, cognitive, and…
ID
Source
Brief title
Condition
- Other condition
Synonym
Health condition
mensen met kanker
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Psychological problems are the long-term outcome variables and are
conceptualized as psychological symptomathology as described in DSM-IV axis-I
(e.g., affective disorders) and the Global Functioning Scale.
Secondary outcome
In addition to insight in the prevalence of psychological problems (i.e.,
partial DSM-IV, axis-I disorders) in cancer patients, the study will offer
information about (i) the intermediate stages of the adaptation process, (ii)
risk factors for maladjustemnt and (iii) it will offer preliminary information
for the development of interventions that do take individual differences into
account.
Background summary
Cancer diagnosis, treatment and subsequent changes in life are well known to
cause emotional distress in people. Although most individuals with cancer are
able to adapt to the changes and losses imposed by the illness, others (25-30
%) develop clinically significant problems (e.g., mood and anxiety
disorders)(Carlson & Bultz, 2004). One of the key goals in psychosocial
oncology is to determine why some people are able to adapt to cancer while
others continue to suffer. Insight in the determinants of these individual
differences is necessary to design optimal interventions. One of the most
widely accepted theories in psychosocial oncology is the stress-coping theory.
This theory is limited, however, by inconsistencies, in the ability to explain
individual differences and in bridging the gap between theory and praxis
(Brennan, 2001; Somerfield & McCrae, 2000).
Study objective
The purpose of the proposed study is twofold. First, to test a process model of
adaptation that distinguishes between the changes in life imposed by the
illness (i.e., subjective cancer experience), the immediate (emotional,
cognitive, and behvaioral) responses to these changes, and the psychosocial
problems that may develop when the immediate responses persist beyond their
adaptive benefit. Second, to investigate individual differences in the
adaptation process by including intra- and interpersonal factors that may put
people at risk for maladjustment. When risk factors can be identified it may be
possible to prevent psychological problems and it may provide clues for how to
treat psychological problems in oncology.
Study design
In this 4-year prospective study we will follow newely diagnosed cancer
patients for 12 months. To be able to assess when and how stressors evolve into
psychological problems, assessment will be done every three months, with a
total of five assessment points.
Study burden and risks
Both self-report measures and structured (clinical) interviews will be used in
order to gain fuller insight in the adaptation processes. A structured
interview will take place at T1 (within three months after diagnosis) and T5
(12 months after T1) and will be conducted by trained psychologist. Self-report
measures will be completed by participants at all assessment point (T1-T5). The
assessment at T1 and T5 will take approximately 60 to 90 minutes and the
intermediate assessments will take approximately 30 to 45 minutes. Total
assessment time over a one year period will be maximal 5 / 6 hours .
A deusinglaan 1
Groningen
NL
A deusinglaan 1
Groningen
NL
Listed location countries
Age
Inclusion criteria
A first diagnosis of cervix, bladder, breast, prostate or colon cancer within the last three months
Expected survival of 1.5 years
Age between 30 and 65 years
Written informed consent
Exclusion criteria
History of cancer
Younger than 30 and older than 65 years
Not able to read or speak dutch fluently
Design
Recruitment
Medical products/devices used
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL12034.042.06 |