The objective of the study is primarily to study functions of gastrocnemius and soleus during gait individually. Secondly, to determine to what degree stimulation of the gastrocnemius and soleus can be achieved, in isolation or in combination, using…
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- Other condition
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Health condition
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Outcome measures
Primary outcome
Kinetic and kinematic parameters such as joint rotations, moments and powers
along with EMG will be primary parameters.
The data will be analysed using the clinical manager for kinetic and kinematic
outcomes. EMG will be analysed to differentiate phasic activity patterns of the
muscles in question The cross correlation analysis will also be carried out to
see if there is any evidence of overlap of EMG between the 2 muscles by
comparing EMG measured with surface and fine wire electrodes.
With electrical stimulation experiments same set of electrodes will be used and
the EMG will be analysed in similar fashion (cross correlation studies) to see
isolation of response to stimulation.
Secondary outcome
There are no secondary outcome parameters.
Background summary
Anatomically gasrocnemius and soleus are grouped together and called triceps
surae. However they consist of 2 distinct muscles, one of which is bi-articular
and the other is mono-articular. The fibre composition of the 2 is also
different. Gastrocnemius has predominantly fast twitch fibres where as soleus
consists predominantly of slow twitch fibres. Functionally these 2 muscles
could be very different. Descriptions found in the literature concerning
function of these 2 muscles state that they function similar to one another.
However, due to close proximity, the surface electrodes placed on gastrocnemius
during gait studies are bound to show cross talk from soleus. The function of
these two muscles could only be differentiated using both, surface and fine
wire electrodes simultaneously.
For some years electrical stimulation of the calf muscles has been considered
as a possible solution for the lack of acceleration during gait in subjects who
have had stroke. However, the attempts to improve their gait have been
unsatisfactory. This may be due to the anatomical and functional differences or
may be due to meer closeness. Generally, implantable electrodes are the most
ideal method for stimulation of muscles in isolation however in many cases they
are not as practical as surface electrodes. The first step in this direction
would be to determine if we can effectively stimulate these underlying muscles
selectively using surface electrodes.
Study objective
The objective of the study is primarily to study functions of gastrocnemius and
soleus during gait individually. Secondly, to determine to what degree
stimulation of the gastrocnemius and soleus can be achieved, in isolation or in
combination, using surface stimulating electrodes.
Study design
Fundamental theory forming observational study.
The use of 3-D measurement system such as VICON and simultaneous use of surface
and fine-wire EMG will help define the exact functions of the two muscles in
kinematic and kinetic terms. The use of surface and fine wire electrodes will
also enable us to explore the extent of cross talk during natural action of the
muscles in question and that during neuromuscular electrical stimulation
After placement EMG electrodes selectivity of the insertion site will be tested
by asking the subject to perform muscle specific movements. Markers will be
placed. The subject will be asked to walk at different walking speeds during
data collection.
For the stimulation part of the study: The muscles will be stimulated using
surface electrodes. Four different stimulation electrode placement
configurations will be examined. Stimulation parameters: biphasic pulses with
pulse duration 350µs, frequency 20 pps, 35 pps & 45 pps. EMG will be recorded
from all electrodes during stimulation
After the data collection the electrodes will be removed.
Study burden and risks
Besides a little discomfort at the time of insertion of fine wire electrodes it
is expected that the subjects will experience no further pain or discomfort. In
general, there will be no health risks involved in participating in the
project. On rare occasions the tip of the fine wire electrode breaks and is
left behind in the muscle, however, due to inert properties of the metal and
being sterile it causes very little problems.
Roessinghsbleekweg 33
7522 AH Enschede
Nederland
Roessinghsbleekweg 33
7522 AH Enschede
Nederland
Listed location countries
Age
Inclusion criteria
Able bodie adults, age between 18 and 65years, without any musculoskeletal abnormalities and normal walking function.
Exclusion criteria
Subjects with gait abnormalities or musculoskeletal abnormalities, younger than 18 or older than 65 years.
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL12104.080.06 |