No registrations found.
ID
Source
Health condition
Patients referred for elective and in-house off pump coronary artery bypass (OPCAB)
Sponsors and support
Intervention
Outcome measures
Primary outcome
The main endpoint of this study is to compare values of strain and strain rate measured with TOE and TTE.
Secondary outcome
The secondary endpoint of this study is to compare systolic and diastolic values measured with TOE and TEE
Background summary
This is an observational prospective pilot study comparing myocardial strain values obtained with both TTE and TOE, involving patients undergoing off pump CABG (OPCAB).
Forty patients undergoing OPCAB will be included in this study. Beside standard clinical practice a transthoracic echocardiography will be performed three times perioperatively, i.e. before induction of anesthesia, before start of surgery, at the end of surgery. TTE data will be compared with TOE data to assess validity of the latter. Near infrared spectroscopy electrodes will be applied on the thorax of the patient, above the heart, outside the surgical field. Data of regional tissue oxygenation will be compared with echocardiographic data.
Patients undergoing this study will not incur any extra risk, beside those from the operation itself
Study objective
The primary endpoint of this study is to assess if myocardial strain and strain rate -measured with tissue Doppler and 2D speckle tracking- determined with TOE is comparable with cardiac strain and strain rate determined with TTE.
Secondary endpoint is to validate echocardiographic systolic and diastolic parameters comparing values obtained with TTE with those obtained with TOE.
Study design
Pre operative
Perioperative
Post operative
Intervention
There will be no medical intervention based on the data obtained with the study.
Inclusion criteria
1. patients older than 18 years
2. patients who can give informed consent
3. ejection fraction (EF) > 50%
4. patients referred for elective and in-house OPCAB
Exclusion criteria
1. patients who are unable to give consent
2. patients < 18 years
3. patients who are already part of another randomized study
4. emergency OPCAB
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL4659 |
| NTR-old | NTR4802 |
| Other | Strain 001 : METc 2013/404 |